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A two-trick pony: lysosomal protease cathepsin B possesses surprising ligase activity

Cathepsin B is an important protease within the lysosome, where it helps recycle proteins to maintain proteostasis. It is also known to degrade proteins elsewhere but has no other known functionality. However, by carefully monitoring peptide digestion with liquid chromatography and mass spectrometry...

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Detalles Bibliográficos
Autores principales:	Lambeth, Tyler R., Dai, Zhefu, Zhang, Yong, Julian, Ryan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	RSC 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291735/ https://www.ncbi.nlm.nih.gov/pubmed/34291207 http://dx.doi.org/10.1039/d0cb00224k

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