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Sequence Preference and Initiator Promiscuity for De Novo DNA Synthesis by Terminal Deoxynucleotidyl Transferase

[Image: see text] The untemplated activity of terminal deoxynucleotidyl transferase (TdT) represents its most appealing feature. Its use is well established in applications aiming for extension of a DNA initiator strand, but a more recent focus points to its potential in enzymatic de novo synthesis...

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Detalles Bibliográficos
Autores principales: Schaudy, Erika, Lietard, Jory, Somoza, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291772/
https://www.ncbi.nlm.nih.gov/pubmed/34156829
http://dx.doi.org/10.1021/acssynbio.1c00142