Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis

Pathophysiological defects in water homeostasis can lead to renal failure. Likewise, common genetic disorders associated with abnormal cytoskeletal dynamics in the kidney collecting ducts and perturbed calcium and cAMP signaling in the ciliary compartment contribute to chronic kidney failure. We sho...

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Detalles Bibliográficos
Autores principales: Gopalan, Janani, Omar, Mitchell H, Roy, Ankita, Cruz, Nelly M, Falcone, Jerome, Jones, Kiana N, Forbush, Katherine A, Himmelfarb, Jonathan, Freedman, Benjamin S, Scott, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291974/
https://www.ncbi.nlm.nih.gov/pubmed/34250905
http://dx.doi.org/10.7554/eLife.67828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291974/
https://www.ncbi.nlm.nih.gov/pubmed/34250905
http://dx.doi.org/10.7554/eLife.67828

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