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Tobacco Smoking Increases Methylation of Polypyrimidine Tract Binding Protein 1 Promoter in Intracranial Aneurysms

DNA methylation at the gene promoter region is reportedly involved in the development of intracranial aneurysm (IA). This study aims to investigate the methylation levels of polypyrimidine tract-binding protein 1 (PTBP1) in IA, as well as its potential to predict IA. Forty-eight patients with IA and...

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Detalles Bibliográficos
Autores principales: Wang, Zhepei, Zhou, Shengjun, Zhao, Jikuang, Nie, Sheng, Sun, Jie, Gao, Xiang, Lenahan, Cameron, Lin, Zhiqin, Huang, Yi, Chen, Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292010/
https://www.ncbi.nlm.nih.gov/pubmed/34295240
http://dx.doi.org/10.3389/fnagi.2021.688179