Cardioprotective Effect of Nec-1 in Rats Subjected to MI/R: Downregulation of Autophagy-Like Cell Death

OBJECTIVE: Necrostatin-1 (Nec-1), an inhibitor of necroptosis, has been reported to protect against myocardial ischemia-reperfusion (MI/R) injury. However, the contribution of the potential antinecroptotic effect of Nec-1 on its infarct limitation and cardiac function improvement effects after MI/R...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Lv, Xuebai, Tian, Jue, Wang, Xiaoliang, Wu, Ye, Liu, Hui Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292081/
https://www.ncbi.nlm.nih.gov/pubmed/34354763
http://dx.doi.org/10.1155/2021/9956814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292081/
https://www.ncbi.nlm.nih.gov/pubmed/34354763
http://dx.doi.org/10.1155/2021/9956814

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