Cargando…

Effects of trypanocidal drugs on DNA synthesis: new insights into melarsoprol growth inhibition

[Figure: see text]

Detalles Bibliográficos
Autores principales:	Larson, Stephen, Carter, McKenzie, Hovel-Miner, Galadriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292159/ https://www.ncbi.nlm.nih.gov/pubmed/33593467 http://dx.doi.org/10.1017/S0031182021000317

Ejemplares similares

A Trypanosoma brucei ORFeome-Based Gain-of-Function Library Identifies Genes That Promote Survival during Melarsoprol Treatment
por: Carter, McKenzie, et al.
Publicado: (2020)

A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive
por: Hovel-Miner, Galadriel, et al.
Publicado: (2016)

Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes
por: da Silva, Marcelo Santos, et al.
Publicado: (2018)

Insights into Ergosterol Peroxide’s Trypanocidal Activity
por: Meza-Menchaca, Thuluz, et al.
Publicado: (2019)

High Failure Rates of Melarsoprol for Sleeping Sickness, Democratic Republic of Congo
por: Robays, Jo, et al.
Publicado: (2008)

Biogenic trypanocidal sesquiterpenes: lead compounds to design future trypanocidal drugs - a mini review
por: Saeidnia, Soodabeh, et al.
Publicado: (2013)

Trypanosomiasis Relapse after Melarsoprol Therapy, Democratic Republic of Congo, 1982–2001
por: Pépin, Jacques, et al.
Publicado: (2005)

Clinical Study on the Melarsoprol-Related Encephalopathic Syndrome: Risk Factors and HLA Association
por: Seixas, Jorge, et al.
Publicado: (2020)

Anti-oxidative trypanocidal drugs, myth or reality
por: Saeidnia, Soodabeh
Publicado: (2013)

Isothermal microcalorimetry – A quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time
por: Gysin, M., et al.
Publicado: (2018)

Melarsoprol Cyclodextrin Inclusion Complexes as Promising Oral Candidates for the Treatment of Human African Trypanosomiasis
por: Rodgers, Jean, et al.
Publicado: (2011)

Design and Synthesis of Brain Penetrant Trypanocidal N-Myristoyltransferase Inhibitors
por: Bayliss, Tracy, et al.
Publicado: (2017)

Safety and Efficacy of the 10-Day Melarsoprol Schedule for the Treatment of Second Stage Rhodesiense Sleeping Sickness
por: Kuepfer, Irene, et al.
Publicado: (2012)

Telomere Length Affects the Frequency and Mechanism of Antigenic Variation in Trypanosoma brucei
por: Hovel-Miner, Galadriel A., et al.
Publicado: (2012)

Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity
por: Elias, Paula Regina, et al.
Publicado: (2016)

Synthesis and Evaluation of Trypanocidal Activity of Chromane-Type Compounds and Acetophenones
por: González, Luis A., et al.
Publicado: (2021)

Aquaporin 2 Mutations in Trypanosoma brucei gambiense Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
por: Graf, Fabrice E., et al.
Publicado: (2013)

Novel therapeutic approach: organic arsenical (melarsoprol) alone or with all-trans -retinoic acid markedly inhibit growth of human breast and prostate cancer cells in vitro and in vivo
por: Koshiuka, K, et al.
Publicado: (2000)

Quinol derivatives as potential trypanocidal agents
por: Capes, Amy, et al.
Publicado: (2012)

An In Vitro Assay for Trypanocidal Activity
por: Rubin, Benjamin Arnold
Publicado: (1948)

Trypanocidal Activity of Flavanone Derivatives
por: Maciel Diogo, Gabriela, et al.
Publicado: (2020)

Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib
por: Steverding, Dietmar, et al.
Publicado: (2009)

The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing
por: Begolo, Daniela, et al.
Publicado: (2018)

Synthesis and “in Vitro” Trypanocidal Activity Evaluation of Some Organo-iron Compounds.
por: e Silva, Máfircio L. A., et al.
Publicado: (2002)

Molecular Design, Synthesis and Trypanocidal Activity of Dipeptidyl Nitriles as Cruzain Inhibitors
por: Avelar, Leandro A. A., et al.
Publicado: (2015)

Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs
por: Meredith, Emma Louise, et al.
Publicado: (2017)

Characterization and trypanocidal activity of a β-lapachone-containing drug carrier
por: Barbosa, Juliana M. C., et al.
Publicado: (2021)

The Trypanocidal Effect of Antibiotic Lactones and of their Analogs
por: Rubin, Benjamin Arnold
Publicado: (1948)

Trypanocidal Activity of Marine Natural Products
por: Jones, Amy J., et al.
Publicado: (2013)

The Trypanocidal Activity of Naphthoquinones: A Review
por: Ventura Pinto, Antônio, et al.
Publicado: (2009)

Trypanocidal Essential Oils: A Review
por: de Morais, Mayara Castro, et al.
Publicado: (2020)

Trypanocidal and leishmanicidal activity of six limonoids
por: Steverding, Dietmar, et al.
Publicado: (2020)

An Update on African Trypanocide Pharmaceutics and Resistance
por: Kasozi, Keneth Iceland, et al.
Publicado: (2022)

Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities
por: Torres, Eva, et al.
Publicado: (2012)

Novel African Trypanocidal Agents: Membrane Rigidifying Peptides
por: Harrington, John M., et al.
Publicado: (2012)

Evaluation of trypanocidal drugs used for human African trypanosomosis against Trypanosoma lewisi
por: Dethoua, Mariette, et al.
Publicado: (2013)

Synthesis and Trypanocidal Activity of Novel 2,4,5-Triaryl-N-Hydroxylimidazole Derivatives
por: da Silva, Ramon Borges, et al.
Publicado: (2013)

Characterization and Trypanocidal Activity of a Novel Pyranaphthoquinone
por: Dantas, Elen Diana, et al.
Publicado: (2017)

Trypanocidal Activity of Long Chain Diamines and Aminoalcohols
por: Legarda-Ceballos, Ana L., et al.
Publicado: (2015)

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs
por: Giordani, Federica, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_44fukk2qq87e3bnia8401j9up3