Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression

Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase that is overexpressed in many cancer types and in vivo studies have shown that vascular endothelial cell FAK expression and FAK-phosphorylation at tyrosine (Y) 397, and subsequently FAK-Y861, are important in tumour angiogenesis. Pericyte...

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Detalles Bibliográficos
Autores principales: Lees, Delphine M., Reynolds, Louise E., Pedrosa, Ana Rita, Roy-Luzarraga, Marina, Hodivala-Dilke, Kairbaan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292267/
https://www.ncbi.nlm.nih.gov/pubmed/33730293
http://dx.doi.org/10.1007/s10456-021-09776-8

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