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Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers

Along with early-onset cancers, multiple primary cancers (MPCs) are likely resulting from increased genetic susceptibility; however, the associated predisposition genes or prevalence of the pathogenic variants genes in MPC patients are often unknown. We screened 71 patients with MPC of the stomach,...

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Detalles Bibliográficos
Autores principales: Choi, Yoon Young, Shin, Su-Jin, Lee, Jae Eun, Madlensky, Lisa, Lee, Seung-Tae, Park, Ji Soo, Jo, Jeong-Hyeon, Kim, Hyunki, Nachmanson, Daniela, Xu, Xiaojun, Noh, Sung Hoon, Cheong, Jae-Ho, Harismendy, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292343/
https://www.ncbi.nlm.nih.gov/pubmed/34285288
http://dx.doi.org/10.1038/s41598-021-94292-4