MARCH8 inhibits influenza A virus infection by targeting viral M2 protein for ubiquitination-dependent degradation in lysosomes

The membrane-associated RING-CH (MARCH) proteins are E3 ligases that regulate the stability of various cellular membrane proteins. MARCH8 has been reported to inhibit the infection of HIV-1 and a few other viruses, thus plays an important role in host antiviral defense. However, the antiviral spectr...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoman, Xu, Fengwen, Ren, Lili, Zhao, Fei, Huang, Yu, Wei, Liang, Wang, Yingying, Wang, Conghui, Fan, Zhangling, Mei, Shan, Song, Jingdong, Zhao, Zhendong, Cen, Shan, Liang, Chen, Wang, Jianwei, Guo, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292393/
https://www.ncbi.nlm.nih.gov/pubmed/34285233
http://dx.doi.org/10.1038/s41467-021-24724-2

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