Cargando…

Exome sequencing identifies novel somatic variants in African American esophageal squamous cell carcinoma

Esophageal cancer has a strikingly low survival rate mainly due to the lack of diagnostic markers for early detection and effective therapies. In the U.S., 75% of individuals diagnosed with esophageal squamous cell carcinoma (ESCC) are of African descent. African American ESCC (AA ESCC) is particula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Erkizan, Hayriye Verda, Sukhadia, Shrey, Natarajan, Thanemozhi G., Marino, Gustavo, Notario, Vicente, Lichy, Jack H., Wadleigh, Robert G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292420/ https://www.ncbi.nlm.nih.gov/pubmed/34285259 http://dx.doi.org/10.1038/s41598-021-94064-0

Ejemplares similares

African-American esophageal squamous cell carcinoma expression profile reveals dysregulation of stress response and detox networks
por: Erkizan, Hayriye Verda, et al.
Publicado: (2017)

Metabolomic and exome sequence analysis reveal novel molecular signatures associated with colorectal cancer relapse
por: Gauba, Robinder, et al.
Publicado: (2012)

Ezrin Enhances EGFR Signaling and Modulates Erlotinib Sensitivity in Non–Small Cell Lung Cancer Cells()
por: Saygideğer-Kont, Yasemin, et al.
Publicado: (2016)

African American exome sequencing identifies potential risk variants at Alzheimer disease loci
por: N'Songo, Aurelie, et al.
Publicado: (2017)

Exome sequencing of Filaggrin and related genes in African-American children with atopic dermatitis
por: Margolis, David J., et al.
Publicado: (2014)

Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians
por: Yadav, Santosh, et al.
Publicado: (2020)

NSAID use and somatic exomic mutations in Barrett’s esophagus
por: Galipeau, Patricia C., et al.
Publicado: (2018)

Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia
por: Ashktorab, Hassan, et al.
Publicado: (2019)

Machine Learning-Based Prediction of Distant Recurrence in Invasive Breast Carcinoma Using Clinicopathological Data: A Cross-Institutional Study
por: Sukhadia, Shrey S., et al.
Publicado: (2023)

RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1
por: Erkizan, Hayriye Verda, et al.
Publicado: (2015)

Correction to: NSAID use and somatic exomic mutations in Barrett’s esophagus
por: Galipeau, Patricia C., et al.
Publicado: (2019)

An Exome-wide Association Study for Type 2 Diabetes–Attributed End-Stage Kidney Disease in African Americans
por: Guan, Meijian, et al.
Publicado: (2018)

MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS
por: Pugh, Trevor J., et al.
Publicado: (2012)

Identification of speckle-type POZ protein somatic mutations in African American prostate cancer
por: Buckles, Eric, et al.
Publicado: (2014)

Exome-wide somatic mutation characterization of small bowel adenocarcinoma
por: Hänninen, Ulrika A., et al.
Publicado: (2018)

Detection of Somatic Mutations in Exome Sequencing of Tumor-only Samples
por: Hsu, Yu-Chin, et al.
Publicado: (2017)

Frequency and signature of somatic variants in 1461 human brain exomes
por: Wei, Wei, et al.
Publicado: (2018)

Identification of somatic alterations in lipoma using whole exome sequencing
por: Kanojia, Deepika, et al.
Publicado: (2019)

Experimental Study of Somatic Variants of Osteosarcoma by Whole-Exome Sequencing
por: Hou, Jingyu, et al.
Publicado: (2020)

Evaluation of Nine Somatic Variant Callers for Detection of Somatic Mutations in Exome and Targeted Deep Sequencing Data
por: Krøigård, Anne Bruun, et al.
Publicado: (2016)

ImaGene: a web-based software platform for tumor radiogenomic evaluation and reporting
por: Sukhadia, Shrey S, et al.
Publicado: (2022)

YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model
por: Minas, Tsion Zewdu, et al.
Publicado: (2015)

Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study
por: Simino, Jeannette, et al.
Publicado: (2017)

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
por: Krauthammer, Michael, et al.
Publicado: (2012)

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
por: Helman, Elena, et al.
Publicado: (2014)

Whole exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas
por: Fishbein, Lauren, et al.
Publicado: (2015)

Improving somatic variant identification through integration of genome and exome data
por: Vijayan, Vinaya, et al.
Publicado: (2017)

Somatic mutations render human exome and pathogen DNA more similar
por: Ebrahimzadeh, Ehsan, et al.
Publicado: (2019)

Human exome sequence data in support of somatic mosaicism in carotid atherosclerosis
por: Sleptcov, Alexei A., et al.
Publicado: (2021)

Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives
por: Akula, Nirmala, et al.
Publicado: (2011)

Comparison of somatic mutation calling methods in amplicon and whole exome sequence data
por: Xu, Huilei, et al.
Publicado: (2014)

Exome-Wide Somatic Microsatellite Variation Is Altered in Cells with DNA Repair Deficiencies
por: Vaksman, Zalman, et al.
Publicado: (2014)

Somatic Genetic Variation in Solid Pseudopapillary Tumor of the Pancreas by Whole Exome Sequencing
por: Guo, Meng, et al.
Publicado: (2017)

Whole exome sequencing reveals novel somatic alterations in neuroblastoma patients with chemotherapy
por: Duan, Chao, et al.
Publicado: (2018)

Exome Evaluation of Autism-Associated Genes in Amazon American Populations
por: da Costa, Giovana E., et al.
Publicado: (2022)

African Ancestry Is Associated with Asthma Risk in African Americans
por: Flores, Carlos, et al.
Publicado: (2012)

Genomic regions associated with susceptibility to Barrett’s esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study
por: Sun, Xiangqing, et al.
Publicado: (2017)

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity
por: Schlottmann, Silke, et al.
Publicado: (2012)

Takotsubo Syndrome in African American vs. Non-African American Women
por: QaQa, Ashraf, et al.
Publicado: (2011)

Failure to Identify Somatic Mutations in Monozygotic Twins Discordant for Schizophrenia by Whole Exome Sequencing
por: Lyu, Nan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_os2bf4ts260920u1p63ggfvs4j