Nanoparticle T-cell engagers as a modular platform for cancer immunotherapy

T-cell-based immunotherapy, such as CAR-T cells and bispecific T-cell engagers (BiTEs), has shown promising clinical outcomes in many cancers; however, these therapies have significant limitations, such as poor pharmacokinetics and the ability to target only one antigen on the cancer cells. In multi...

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Detalles Bibliográficos
Autores principales: Alhallak, Kinan, Sun, Jennifer, Wasden, Katherine, Guenthner, Nicole, O’Neal, Julie, Muz, Barbara, King, Justin, Kohnen, Daniel, Vij, Ravi, Achilefu, Samuel, DiPersio, John F., Azab, Abdel Kareem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292428/
https://www.ncbi.nlm.nih.gov/pubmed/33479469
http://dx.doi.org/10.1038/s41375-021-01127-2

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