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Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)

BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a well-established and standard therapy for patients with symptomatic severe aortic stenosis at moderate or high risk for surgical aortic valve replacement. Recently, it has proven non-inferior in patients with low surgical risk. However,...

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Autores principales: Bahaa, Hesham, Sadek, Yasser, Mostafa, Ahmad E., Kamal, Diaa, Baraka, Mahmoud, Abdelghani, Mohammad, Hassan, Ahmed, Shehata, Ahmed, Abdelhamid, Magdy, Elguindy, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292463/
https://www.ncbi.nlm.nih.gov/pubmed/34283346
http://dx.doi.org/10.1186/s43044-021-00189-y
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author Bahaa, Hesham
Sadek, Yasser
Mostafa, Ahmad E.
Kamal, Diaa
Baraka, Mahmoud
Abdelghani, Mohammad
Hassan, Ahmed
Shehata, Ahmed
Abdelhamid, Magdy
Elguindy, Ahmed
author_facet Bahaa, Hesham
Sadek, Yasser
Mostafa, Ahmad E.
Kamal, Diaa
Baraka, Mahmoud
Abdelghani, Mohammad
Hassan, Ahmed
Shehata, Ahmed
Abdelhamid, Magdy
Elguindy, Ahmed
author_sort Bahaa, Hesham
collection PubMed
description BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a well-established and standard therapy for patients with symptomatic severe aortic stenosis at moderate or high risk for surgical aortic valve replacement. Recently, it has proven non-inferior in patients with low surgical risk. However, due to its high cost, the availability of TAVI is variable worldwide. Our aim was to assess the demographic and clinical characteristics and short-term and long-term outcome of those patients. A medical registry is believed to be an excellent tool to perform a field analysis of patients’ course, documenting short, intermediate, and long-term outcomes. This is the first registry for patients who underwent TAVI in Egypt. RESULTS: Ninety-six patients were included in the study; some were retrospective, and the majority were prospective from 5 different cardiac centers from August 2012 till December 2017. The mean age of patients was 77 years SD ± 7.29; females were 52% of the patients and most of the patients were overweight (BMI 30.74, SD ± 6.83). Sixty-three percent of the patients were frail with Katz index ≤ 5. 3.5% had atrial fibrillation (AF) at presentation. General anesthesia was conducted in only 59.37% of the patients. Transfemoral access was the prevailing route of implantation (90%). The median hospital stay was 4 days. In-hospital and 30 days mortality was only 4.16%. CONCLUSION: TAVI outcome in Egypt appeared to be very promising with in-hospital complication, and mortality rates being comparable to international registries (4.16% vs. 4.0% in TVT registry) denoting the procedure as safe and beneficial. Establishing a national registry is critical to highlighting strength and weaknesses as well as identifying key areas for improvements. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s43044-021-00189-y.
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spelling pubmed-82924632021-08-05 Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR) Bahaa, Hesham Sadek, Yasser Mostafa, Ahmad E. Kamal, Diaa Baraka, Mahmoud Abdelghani, Mohammad Hassan, Ahmed Shehata, Ahmed Abdelhamid, Magdy Elguindy, Ahmed Egypt Heart J Research BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a well-established and standard therapy for patients with symptomatic severe aortic stenosis at moderate or high risk for surgical aortic valve replacement. Recently, it has proven non-inferior in patients with low surgical risk. However, due to its high cost, the availability of TAVI is variable worldwide. Our aim was to assess the demographic and clinical characteristics and short-term and long-term outcome of those patients. A medical registry is believed to be an excellent tool to perform a field analysis of patients’ course, documenting short, intermediate, and long-term outcomes. This is the first registry for patients who underwent TAVI in Egypt. RESULTS: Ninety-six patients were included in the study; some were retrospective, and the majority were prospective from 5 different cardiac centers from August 2012 till December 2017. The mean age of patients was 77 years SD ± 7.29; females were 52% of the patients and most of the patients were overweight (BMI 30.74, SD ± 6.83). Sixty-three percent of the patients were frail with Katz index ≤ 5. 3.5% had atrial fibrillation (AF) at presentation. General anesthesia was conducted in only 59.37% of the patients. Transfemoral access was the prevailing route of implantation (90%). The median hospital stay was 4 days. In-hospital and 30 days mortality was only 4.16%. CONCLUSION: TAVI outcome in Egypt appeared to be very promising with in-hospital complication, and mortality rates being comparable to international registries (4.16% vs. 4.0% in TVT registry) denoting the procedure as safe and beneficial. Establishing a national registry is critical to highlighting strength and weaknesses as well as identifying key areas for improvements. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s43044-021-00189-y. Springer Berlin Heidelberg 2021-07-20 /pmc/articles/PMC8292463/ /pubmed/34283346 http://dx.doi.org/10.1186/s43044-021-00189-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Bahaa, Hesham
Sadek, Yasser
Mostafa, Ahmad E.
Kamal, Diaa
Baraka, Mahmoud
Abdelghani, Mohammad
Hassan, Ahmed
Shehata, Ahmed
Abdelhamid, Magdy
Elguindy, Ahmed
Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title_full Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title_fullStr Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title_full_unstemmed Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title_short Early results from an Egyptian transcatheter aortic valve registry (Egy-TVR)
title_sort early results from an egyptian transcatheter aortic valve registry (egy-tvr)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292463/
https://www.ncbi.nlm.nih.gov/pubmed/34283346
http://dx.doi.org/10.1186/s43044-021-00189-y
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