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Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears
Electroadhesion, i.e., adhesion induced by an electric field, occurs between non-sticky cationic and anionic hydrogels. Here, we demonstrate electroadhesion between cationic gels and animal (bovine) tissues. When gel and tissue are placed under an electric field (DC, 10 V) for 20 s, the pair strongl...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292548/ https://www.ncbi.nlm.nih.gov/pubmed/34285208 http://dx.doi.org/10.1038/s41467-021-24022-x |
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author | Borden, Leah K. Gargava, Ankit Raghavan, Srinivasa R. |
author_facet | Borden, Leah K. Gargava, Ankit Raghavan, Srinivasa R. |
author_sort | Borden, Leah K. |
collection | PubMed |
description | Electroadhesion, i.e., adhesion induced by an electric field, occurs between non-sticky cationic and anionic hydrogels. Here, we demonstrate electroadhesion between cationic gels and animal (bovine) tissues. When gel and tissue are placed under an electric field (DC, 10 V) for 20 s, the pair strongly adhere, and the adhesion persists indefinitely thereafter. Applying the DC field with reversed polarity eliminates the adhesion. Electroadhesion works with the aorta, cornea, lung, and cartilage. We demonstrate the use of electroadhesion to seal cuts or tears in tissues or model anionic gels. Electroadhered gel-patches provide a robust seal over openings in bovine aorta, and a gel sleeve is able to rejoin pieces of a severed gel tube. These studies raise the possibility of using electroadhesion in surgery while obviating the need for sutures. Advantages include the ability to achieve adhesion on-command, and moreover the ability to reverse this adhesion in case of error. |
format | Online Article Text |
id | pubmed-8292548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-82925482021-07-23 Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears Borden, Leah K. Gargava, Ankit Raghavan, Srinivasa R. Nat Commun Article Electroadhesion, i.e., adhesion induced by an electric field, occurs between non-sticky cationic and anionic hydrogels. Here, we demonstrate electroadhesion between cationic gels and animal (bovine) tissues. When gel and tissue are placed under an electric field (DC, 10 V) for 20 s, the pair strongly adhere, and the adhesion persists indefinitely thereafter. Applying the DC field with reversed polarity eliminates the adhesion. Electroadhesion works with the aorta, cornea, lung, and cartilage. We demonstrate the use of electroadhesion to seal cuts or tears in tissues or model anionic gels. Electroadhered gel-patches provide a robust seal over openings in bovine aorta, and a gel sleeve is able to rejoin pieces of a severed gel tube. These studies raise the possibility of using electroadhesion in surgery while obviating the need for sutures. Advantages include the ability to achieve adhesion on-command, and moreover the ability to reverse this adhesion in case of error. Nature Publishing Group UK 2021-07-20 /pmc/articles/PMC8292548/ /pubmed/34285208 http://dx.doi.org/10.1038/s41467-021-24022-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Borden, Leah K. Gargava, Ankit Raghavan, Srinivasa R. Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title | Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title_full | Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title_fullStr | Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title_full_unstemmed | Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title_short | Reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
title_sort | reversible electroadhesion of hydrogels to animal tissues for suture-less repair of cuts or tears |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292548/ https://www.ncbi.nlm.nih.gov/pubmed/34285208 http://dx.doi.org/10.1038/s41467-021-24022-x |
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