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TOX defines the degree of CD8+ T cell dysfunction in distinct phases of chronic HBV infection

OBJECTIVE: Chronic hepatitis B virus (HBV) infection is characterised by HBV-specific CD8+ T cell dysfunction that has been linked to Tcell exhaustion, a distinct differentiation programme associated with persisting antigen recognition. Recently, Thymocyte Selection-Associated High Mobility Group Bo...

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Detalles Bibliográficos
Autores principales:	Heim, Kathrin, Binder, Benedikt, Sagar, Wieland, Dominik, Hensel, Nina, Llewellyn-Lacey, Sian, Gostick, Emma, Price, David A., Emmerich, Florian, Vingerhoet, Hildegard, Kraft, Anke R M, Cornberg, Markus, Boettler, Tobias, Neumann-Haefelin, Christoph, Zehn, Dietmar, Bengsch, Bertram, Hofmann, Maike, Thimme, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Hepatology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292571/ https://www.ncbi.nlm.nih.gov/pubmed/33097558 http://dx.doi.org/10.1136/gutjnl-2020-322404

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