Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease

OBJECTIVE: Haemorrhoidal disease (HEM) affects a large and silently suffering fraction of the population but its aetiology, including suspected genetic predisposition, is poorly understood. We report the first genome-wide association study (GWAS) meta-analysis to identify genetic risk factors for HE...

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Detalles Bibliográficos
Autores principales: Zheng, Tenghao, Ellinghaus, David, Juzenas, Simonas, Cossais, François, Burmeister, Greta, Mayr, Gabriele, Jørgensen, Isabella Friis, Teder-Laving, Maris, Skogholt, Anne Heidi, Chen, Sisi, Strege, Peter R, Ito, Go, Banasik, Karina, Becker, Thomas, Bokelmann, Frank, Brunak, Søren, Buch, Stephan, Clausnitzer, Hartmut, Datz, Christian, Degenhardt, Frauke, Doniec, Marek, Erikstrup, Christian, Esko, Tõnu, Forster, Michael, Frey, Norbert, Fritsche, Lars G, Gabrielsen, Maiken Elvestad, Gräßle, Tobias, Gsur, Andrea, Gross, Justus, Hampe, Jochen, Hendricks, Alexander, Hinz, Sebastian, Hveem, Kristian, Jongen, Johannes, Junker, Ralf, Karlsen, Tom Hemming, Hemmrich-Stanisak, Georg, Kruis, Wolfgang, Kupcinskas, Juozas, Laubert, Tilman, Rosenstiel, Philip C, Röcken, Christoph, Laudes, Matthias, Leendertz, Fabian H, Lieb, Wolfgang, Limperger, Verena, Margetis, Nikolaos, Mätz-Rensing, Kerstin, Németh, Christopher Georg, Ness-Jensen, Eivind, Nowak-Göttl, Ulrike, Pandit, Anita, Pedersen, Ole Birger, Peleikis, Hans Günter, Peuker, Kenneth, Rodriguez, Cristina Leal, Rühlemann, Malte Christoph, Schniewind, Bodo, Schulzky, Martin, Skieceviciene, Jurgita, Tepel, Jürgen, Thomas, Laurent, Uellendahl-Werth, Florian, Ullum, Henrik, Vogel, Ilka, Volzke, Henry, von Fersen, Lorenzo, von Schönfels, Witigo, Vanderwerff, Brett, Wilking, Julia, Wittig, Michael, Zeissig, Sebastian, Zobel, Myrko, Zawistowski, Matthew, Vacic, Vladimir, Sazonova, Olga, Noblin, Elizabeth S, Farrugia, Gianrico, Beyder, Arthur, Wedel, Thilo, Kahlke, Volker, Schafmayer, Clemens, D'Amato, Mauro, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Colon
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292596/
https://www.ncbi.nlm.nih.gov/pubmed/33888516
http://dx.doi.org/10.1136/gutjnl-2020-323868

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