Cargando…

Possible Regulation of bFGF Expression by Mast Cells in Osteoarthritis Patients with Obesity: A Cross-Sectional Study

PURPOSE: Obesity is associated with the risk of developing knee osteoarthritis (KOA). Furthermore, synovial basic fibroblast growth factor (bFGF) is linked to the severity of KOA. We previously demonstrated that bFGF and mast cell (MC) marker expression were elevated in the synovial tissues (ST) of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Takata, Ken, Uchida, Kentaro, Takano, Shotaro, Mukai, Manabu, Inoue, Gen, Sekiguchi, Hiroyuki, Aikawa, Jun, Miyagi, Masayuki, Iwase, Dai, Takaso, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292626/ https://www.ncbi.nlm.nih.gov/pubmed/34295170 http://dx.doi.org/10.2147/DMSO.S319537

Ejemplares similares

Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee
por: Takata, Ken, et al.
Publicado: (2020)

Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients
por: Tsukada, Ayumi, et al.
Publicado: (2022)

Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia
por: Mukai, Manabu, et al.
Publicado: (2018)

Expression of calcitonin gene-related peptide in the infrapatellar fat pad in knee osteoarthritis patients
por: Aikawa, Jun, et al.
Publicado: (2017)

Increase in mast cell marker expression in the synovium of obese patients with osteoarthritis of the knee
por: Uchida, Kentaro, et al.
Publicado: (2019)

Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis
por: Aikawa, Jun, et al.
Publicado: (2018)

Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis
por: Takano, Shotaro, et al.
Publicado: (2018)

Increase in CD5L expression in the synovial membrane of knee osteoarthritis patients with obesity
por: Shoji, Shintaro, et al.
Publicado: (2021)

Increase and regulation of synovial calcitonin gene-related peptide expression in patients with painful knee osteoarthritis
por: Takano, Shotaro, et al.
Publicado: (2017)

Unilateral-dominant reduction in muscle volume in female knee osteoarthritis patients: computed tomography-based analysis of bilateral sides
por: Tsukada, Ayumi, et al.
Publicado: (2020)

Elevated macrophage-inducible C-type lectin expression in the synovial tissue of patients with rheumatoid arthritis
por: Takata, Ken, et al.
Publicado: (2021)

Vascular Endothelial Growth Factor Is Regulated by the Canonical and Noncanonical Transforming Growth Factor-β Pathway in Synovial Fibroblasts Derived from Osteoarthritis Patients
por: Takano, Shotaro, et al.
Publicado: (2019)

Transforming growth factor-β stimulates nerve growth factor production in osteoarthritic synovium
por: Takano, Shotaro, et al.
Publicado: (2019)

Differential Synovial CGRP/RAMP1 Expression in Men and Women With Knee Osteoarthritis
por: Uchida, Kentaro, et al.
Publicado: (2021)

β2-microglobulin alters the profiles of inflammatory cytokines and of matrix metalloprotease in macrophages derived from the osteoarthritic synovium
por: Muneshige, Kyoko, et al.
Publicado: (2023)

Activation of calcitonin gene-related peptide signaling through the prostaglandin E2-EP1/EP2/EP4 receptor pathway in synovium of knee osteoarthritis patients
por: Minatani, Atsushi, et al.
Publicado: (2016)

Osteoarthritis patients with high haemoglobin A1c have increased Toll-like receptor 4 and matrix metalloprotease-13 expression in the synovium
por: Murata, Kosuke, et al.
Publicado: (2019)

Adrenomedullin Regulates IL-1β Gene Expression in F4/80+ Macrophages during Synovial Inflammation
por: Takano, Shotaro, et al.
Publicado: (2017)

Using allogenous structural bone graft for uncontained tibial bone defects ≥ 10 mm in depth in primary total knee arthroplasty
por: Iwase, Dai, et al.
Publicado: (2022)

Nerve Growth Factor Regulation by TNF-α and IL-1β in Synovial Macrophages and Fibroblasts in Osteoarthritic Mice
por: Takano, Shotaro, et al.
Publicado: (2016)

Expression and regulation of macrophage-inducible C-type lectin in human synovial macrophages
por: Moriya, Mitsutoshi, et al.
Publicado: (2021)

Hyaluronic Acid (800 kDa) Supplementation of University of Wisconsin Solution Improves Viability of Osteochondral Grafts and Reduces Matrix Metalloproteinase Expression during Cold Preservation
por: Yamada, Takuya, et al.
Publicado: (2015)

Transforming growth factor activating kinase 1 regulates extracellular matrix degrading enzymes and pain-related molecule expression following tumor necrosis factor-α stimulation of synovial cells: an in vitro study
por: Uchida, Kentaro, et al.
Publicado: (2017)

CD39+CD55− Fb Subset Exhibits Myofibroblast-Like Phenotype and Is Associated with Pain in Osteoarthritis of the Knee
por: Tsuchiya, Maho, et al.
Publicado: (2023)

Regulation of Tumor Necrosis Factor-α by Peptide Lv in Bone Marrow Macrophages and Synovium
por: Mukai, Manabu, et al.
Publicado: (2021)

Basic Fibroblast Growth Factor-Anchored Multilayered Mesenchymal Cell Sheets Accelerate Periosteal Bone Formation
por: Uchida, Kentaro, et al.
Publicado: (2017)

Acceleration of bone union by in situ-formed hydrogel containing bone morphogenetic protein-2 in a mouse refractory fracture model
por: Shoji, Shintaro, et al.
Publicado: (2020)

Origin of M2 Mϕ and its macrophage polarization by TGF-β in a mice intervertebral injury model
por: Kawakubo, Ayumu, et al.
Publicado: (2022)

Loop-Mediated Isothermal Amplification Screening for COVID-19 in Asymptomatic Preoperative Orthopedic Patients in a General Hospital in Kanagawa, Japan
por: Uchida, Kentaro, et al.
Publicado: (2020)

Elevated leptin levels induce inflammation through IL-6 in skeletal muscle of aged female rats
por: Tazawa, Ryo, et al.
Publicado: (2019)

Acceleration of Bone Healing by In Situ-Forming Dextran-Tyramine Conjugates Containing Basic Fibroblast Growth Factor in Mice
por: Shoji, Shintaro, et al.
Publicado: (2020)

Reduced TGF-β Expression and CD206-Positive Resident Macrophages in the Intervertebral Discs of Aged Mice
por: Yokozeki, Yuji, et al.
Publicado: (2021)

Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion
por: Kuroda, Akiyoshi, et al.
Publicado: (2022)

Mechanisms of Peripheral and Central Sensitization in Osteoarthritis Pain
por: Ohashi, Yoshihisa, et al.
Publicado: (2023)

Spontaneous Spinal Epidural Hematoma in an Infant with Developmental Disabilities
por: Mukai, Manabu, et al.
Publicado: (2018)

Management of regional bone bank during declaration of a state of emergency concerning the COVID-19 in Japan
por: Uchida, Kentaro, et al.
Publicado: (2021)

Experience of an Orthopaedic Surgery Department Early During the COVID-19 Outbreak in Japan Including Real-Time Polymerase Chain Reaction Assay Results for SARS-CoV-2
por: Inoue, Gen, et al.
Publicado: (2020)

Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen-binding domain fusion protein combined with allogenic demineralized bone powder
por: Saito, Wataru, et al.
Publicado: (2015)

Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells
Publicado: (1994)

A Modified Sliding-Lengthening Approach to Tendon Lengthening with a Locking Mechanism Suture: A Technical Note
por: Iwase, Dai, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5usfibll88hijcjjfc89r1ung5