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α-Synuclein: An All-Inclusive Trip Around its Structure, Influencing Factors and Applied Techniques
Alpha-synuclein (αSyn) is a highly expressed and conserved protein, typically found in the presynaptic terminals of neurons. The misfolding and aggregation of αSyn into amyloid fibrils is a pathogenic hallmark of several neurodegenerative diseases called synucleinopathies, such as Parkinson’s diseas...
Autores principales: | Bisi, Nicolò, Feni, Lucia, Peqini, Kaliroi, Pérez-Peña, Helena, Ongeri, Sandrine, Pieraccini, Stefano, Pellegrino, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292672/ https://www.ncbi.nlm.nih.gov/pubmed/34307295 http://dx.doi.org/10.3389/fchem.2021.666585 |
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