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MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone

Multiple sclerosis (MS) is a progressive autoimmune disease characterized by T-cell mediated demyelination in central nervous system (CNS). Experimental autoimmune encephalomyelitis (EAE) is a widely used in vivo disease model of MS. Glucocorticoids such as dexamethasone (dex) function as immunosupp...

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Detalles Bibliográficos
Autores principales: Nam, Jinhan, Koppinen, Tapani K., Voutilainen, Merja H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292680/
https://www.ncbi.nlm.nih.gov/pubmed/34305531
http://dx.doi.org/10.3389/fncel.2021.640084