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Commissioning of and preliminary experience with a new fully integrated computed tomography linac

PURPOSE: A new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT‐linac 506c, was introduced into clinical application in 2019 by United Imaging Healthcare (UIH) Co., Ltd. (Shanghai, China). It combines a Carm linac with a diagnostic‐quality 16‐slic...

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Autores principales: Yu, Lei, Zhao, Jun, Zhang, Zhen, Wang, Jiazhou, Hu, Weigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292712/
https://www.ncbi.nlm.nih.gov/pubmed/34151504
http://dx.doi.org/10.1002/acm2.13313
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author Yu, Lei
Zhao, Jun
Zhang, Zhen
Wang, Jiazhou
Hu, Weigang
author_facet Yu, Lei
Zhao, Jun
Zhang, Zhen
Wang, Jiazhou
Hu, Weigang
author_sort Yu, Lei
collection PubMed
description PURPOSE: A new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT‐linac 506c, was introduced into clinical application in 2019 by United Imaging Healthcare (UIH) Co., Ltd. (Shanghai, China). It combines a Carm linac with a diagnostic‐quality 16‐slice CT imager, providing seamless workflow from simulation to treatment. The aim of this report is to assess the technical characteristics, commissioning results and preliminary experiences stemming from clinical usage. METHODS: The mechanical and imaging test procedures, commissioning data collection and TPS validation were summarized. CTIGRT accuracy was investigated with different loads and couch extensions. A series of end‐to‐end cases for different treatment sites and delivery techniques were tested preclinically to estimate the overall accuracy for the entire treatment scheme. The results of patient‐specific QA and machine stability during a one‐year operation are also reported. RESULTS: Gantry/couch/collimator isocentricity was measured as 0.63 mm in radius. The TPS models were in agreement with the beam commissioning data within a deviation of 2%. An overall submillimeter accuracy was demonstrated for the CT‐IGRT process under all conditions. The absolute point dose difference for all the preclinical end‐to‐end tests was within 3%, and the gamma passing rate of the 2D dose distribution measured by EBT3 film was better than 90% (3% DD, 3 mm DTA and 10% threshold). Pretreatment QA of clinical cases resulted with better than 3% point dose difference and more than 99% gamma passing rate (3% DD/2 mm DTA/10% threshold) tested with Delta4. The output of the linac was mostly within 1% of variation in a one‐year operation. CONCLUSION: The commissioning results and clinical QA results show that the uRT‐linac 506c platform exhibits good and stable performance in mechanical and dosimetric accuracy. The integrated CT system provides an efficient workflow for image guidance with submillimeter localization precision, and will be a good starting point to proceed advanced adaptive radiotherapy.
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spelling pubmed-82927122021-07-22 Commissioning of and preliminary experience with a new fully integrated computed tomography linac Yu, Lei Zhao, Jun Zhang, Zhen Wang, Jiazhou Hu, Weigang J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: A new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT‐linac 506c, was introduced into clinical application in 2019 by United Imaging Healthcare (UIH) Co., Ltd. (Shanghai, China). It combines a Carm linac with a diagnostic‐quality 16‐slice CT imager, providing seamless workflow from simulation to treatment. The aim of this report is to assess the technical characteristics, commissioning results and preliminary experiences stemming from clinical usage. METHODS: The mechanical and imaging test procedures, commissioning data collection and TPS validation were summarized. CTIGRT accuracy was investigated with different loads and couch extensions. A series of end‐to‐end cases for different treatment sites and delivery techniques were tested preclinically to estimate the overall accuracy for the entire treatment scheme. The results of patient‐specific QA and machine stability during a one‐year operation are also reported. RESULTS: Gantry/couch/collimator isocentricity was measured as 0.63 mm in radius. The TPS models were in agreement with the beam commissioning data within a deviation of 2%. An overall submillimeter accuracy was demonstrated for the CT‐IGRT process under all conditions. The absolute point dose difference for all the preclinical end‐to‐end tests was within 3%, and the gamma passing rate of the 2D dose distribution measured by EBT3 film was better than 90% (3% DD, 3 mm DTA and 10% threshold). Pretreatment QA of clinical cases resulted with better than 3% point dose difference and more than 99% gamma passing rate (3% DD/2 mm DTA/10% threshold) tested with Delta4. The output of the linac was mostly within 1% of variation in a one‐year operation. CONCLUSION: The commissioning results and clinical QA results show that the uRT‐linac 506c platform exhibits good and stable performance in mechanical and dosimetric accuracy. The integrated CT system provides an efficient workflow for image guidance with submillimeter localization precision, and will be a good starting point to proceed advanced adaptive radiotherapy. John Wiley and Sons Inc. 2021-06-20 /pmc/articles/PMC8292712/ /pubmed/34151504 http://dx.doi.org/10.1002/acm2.13313 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Yu, Lei
Zhao, Jun
Zhang, Zhen
Wang, Jiazhou
Hu, Weigang
Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title_full Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title_fullStr Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title_full_unstemmed Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title_short Commissioning of and preliminary experience with a new fully integrated computed tomography linac
title_sort commissioning of and preliminary experience with a new fully integrated computed tomography linac
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292712/
https://www.ncbi.nlm.nih.gov/pubmed/34151504
http://dx.doi.org/10.1002/acm2.13313
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