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Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator

PURPOSE: Establish and compare two metrics for monitoring beam energy changes in the Halcyon platform and evaluate the accuracy of these metrics across multiple Halcyon linacs. METHOD: The first energy metric is derived from the diagonal normalized flatness (F(DN)), which is defined as the ratio of...

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Autores principales: Gao, Song, Chetvertkov, Mikhail A., Cai, Bin, Dwivedi, Abhishek, Mihailidis, Dimitris, Ray, Xenia, Netherton, Tucker, Court, Laurence E., Simon, William E., Balter, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292713/
https://www.ncbi.nlm.nih.gov/pubmed/34042271
http://dx.doi.org/10.1002/acm2.13281
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author Gao, Song
Chetvertkov, Mikhail A.
Cai, Bin
Dwivedi, Abhishek
Mihailidis, Dimitris
Ray, Xenia
Netherton, Tucker
Court, Laurence E.
Simon, William E.
Balter, Peter A.
author_facet Gao, Song
Chetvertkov, Mikhail A.
Cai, Bin
Dwivedi, Abhishek
Mihailidis, Dimitris
Ray, Xenia
Netherton, Tucker
Court, Laurence E.
Simon, William E.
Balter, Peter A.
author_sort Gao, Song
collection PubMed
description PURPOSE: Establish and compare two metrics for monitoring beam energy changes in the Halcyon platform and evaluate the accuracy of these metrics across multiple Halcyon linacs. METHOD: The first energy metric is derived from the diagonal normalized flatness (F(DN)), which is defined as the ratio of the average measurements at a fixed off‐axis equal distance along the open profiles in two diagonals to the measurement at the central axis with an ionization chamber array (ICA). The second energy metric comes from the area ratio (AR) of the quad wedge (QW) profiles measured with the QW on the top of the ICA. Beam energy is changed by adjusting the magnetron current in a non‐clinical Halcyon. With D(10cm) measured in water at each beam energy, the relationships between F(DN) or AR energy metrics to D(10cm) in water is established with linear regression across six energy settings. The coefficients from these regressions allow D(10cm)(F(DN)) calculation from F(DN) using open profiles and D(10cm)(QW) calculation from AR using QW profiles. RESULTS: Five Halcyon linacs from five institutions were used to evaluate the accuracy of the D(10cm)(F(DN)) and the D(10cm)(QW) energy metrics by comparing to the D(10cm) values computed from the treatment planning system (TPS) and D(10cm) measured in water. For the five linacs, the D(10cm)(F(DN)) reported by the ICA based on F(DN) from open profiles agreed with that calculated by TPS within –0.29 ± 0.23% and 0.61% maximum discrepancy; the D(10cm)(QW) reported by the QW profiles agreed with that calculated by TPS within –0.82 ± 1.27% and –2.43% maximum discrepancy. CONCLUSION: The F(DN)‐based energy metric D(10cm)(F(DN)) can be used for acceptance testing of beam energy, and also for the verification of energy in periodic quality assurance (QA) processes.
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spelling pubmed-82927132021-07-22 Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator Gao, Song Chetvertkov, Mikhail A. Cai, Bin Dwivedi, Abhishek Mihailidis, Dimitris Ray, Xenia Netherton, Tucker Court, Laurence E. Simon, William E. Balter, Peter A. J Appl Clin Med Phys Radiation Oncology Physics PURPOSE: Establish and compare two metrics for monitoring beam energy changes in the Halcyon platform and evaluate the accuracy of these metrics across multiple Halcyon linacs. METHOD: The first energy metric is derived from the diagonal normalized flatness (F(DN)), which is defined as the ratio of the average measurements at a fixed off‐axis equal distance along the open profiles in two diagonals to the measurement at the central axis with an ionization chamber array (ICA). The second energy metric comes from the area ratio (AR) of the quad wedge (QW) profiles measured with the QW on the top of the ICA. Beam energy is changed by adjusting the magnetron current in a non‐clinical Halcyon. With D(10cm) measured in water at each beam energy, the relationships between F(DN) or AR energy metrics to D(10cm) in water is established with linear regression across six energy settings. The coefficients from these regressions allow D(10cm)(F(DN)) calculation from F(DN) using open profiles and D(10cm)(QW) calculation from AR using QW profiles. RESULTS: Five Halcyon linacs from five institutions were used to evaluate the accuracy of the D(10cm)(F(DN)) and the D(10cm)(QW) energy metrics by comparing to the D(10cm) values computed from the treatment planning system (TPS) and D(10cm) measured in water. For the five linacs, the D(10cm)(F(DN)) reported by the ICA based on F(DN) from open profiles agreed with that calculated by TPS within –0.29 ± 0.23% and 0.61% maximum discrepancy; the D(10cm)(QW) reported by the QW profiles agreed with that calculated by TPS within –0.82 ± 1.27% and –2.43% maximum discrepancy. CONCLUSION: The F(DN)‐based energy metric D(10cm)(F(DN)) can be used for acceptance testing of beam energy, and also for the verification of energy in periodic quality assurance (QA) processes. John Wiley and Sons Inc. 2021-05-27 /pmc/articles/PMC8292713/ /pubmed/34042271 http://dx.doi.org/10.1002/acm2.13281 Text en © 2021 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Gao, Song
Chetvertkov, Mikhail A.
Cai, Bin
Dwivedi, Abhishek
Mihailidis, Dimitris
Ray, Xenia
Netherton, Tucker
Court, Laurence E.
Simon, William E.
Balter, Peter A.
Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title_full Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title_fullStr Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title_full_unstemmed Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title_short Beam energy metrics for the acceptance and quality assurance of Halcyon linear accelerator
title_sort beam energy metrics for the acceptance and quality assurance of halcyon linear accelerator
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292713/
https://www.ncbi.nlm.nih.gov/pubmed/34042271
http://dx.doi.org/10.1002/acm2.13281
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