Cargando…
Epigenetic Mechanisms in DNA Double Strand Break Repair: A Clinical Review
Upon the induction of DNA damage, the chromatin structure unwinds to allow access to enzymes to catalyse the repair. The regulation of the winding and unwinding of chromatin occurs via epigenetic modifications, which can alter gene expression without changing the DNA sequence. Epigenetic mechanisms...
Autores principales: | Fernandez, Alejandra, O’Leary, Connor, O’Byrne, Kenneth J, Burgess, Joshua, Richard, Derek J, Suraweera, Amila |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292790/ https://www.ncbi.nlm.nih.gov/pubmed/34307454 http://dx.doi.org/10.3389/fmolb.2021.685440 |
Ejemplares similares
-
Chemotherapeutic Compounds Targeting the DNA Double-Strand Break Repair Pathways: The Good, the Bad, and the Promising
por: Jekimovs, Christian, et al.
Publicado: (2014) -
COMMD1, from the Repair of DNA Double Strand Breaks, to a Novel Anti-Cancer Therapeutic Target
por: Suraweera, Amila, et al.
Publicado: (2021) -
Studying DNA Double-Strand Break Repair: An Ever-Growing Toolbox
por: Vítor, Alexandra C., et al.
Publicado: (2020) -
The Emerging Role of RNA Modifications in DNA Double-Strand Break Repair
por: Jimeno, Sonia, et al.
Publicado: (2021) -
The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair
por: Sobanski, Thais, et al.
Publicado: (2023)