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Epigenetically inactivated RASSF1A as a tumor biomarker

RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated by mutations, loss of heterozygosity, and, most commonly, by promoter hypermethylation. Epigenetic inactivation of RASSF1A...

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Detalles Bibliográficos
Autores principales: Raos, Dora, Ulamec, Monika, Bojanac, Ana Katusic, Bulic-Jakus, Floriana, Jezek, Davor, Sincic, Nino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292865/
https://www.ncbi.nlm.nih.gov/pubmed/33175673
http://dx.doi.org/10.17305/bjbms.2020.5219