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Stomach-specific c-Myc overexpression drives gastric adenoma in mice through AKT/mammalian target of rapamycin signaling

Gastric cancer (GC) is one of the most common malignant cancers in the world. c-Myc, a well-known oncogene, is commonly amplified in many cancers, including GC. However, it is still not completely understood how c-Myc functions in GC. Here, we generated a stomach-specific c-Myc transgenic mouse mode...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Feng, Wenxin, Liu, Min, Rao, Hanyu, Li, Xiaoxue, Teng, Yan, Yang, Xiao, Xu, Jin, Gao, Wei-Qiang, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292868/
https://www.ncbi.nlm.nih.gov/pubmed/33259779
http://dx.doi.org/10.17305/bjbms.2020.4978