Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration

Somatic cell reprogramming and tissue repair share relevant factors and molecular programs. Here, Dickkopf‐3 (DKK3) is identified as novel factor for organ regeneration using combined transcription‐factor‐induced reprogramming and RNA‐interference techniques. Loss of Dkk3 enhances the generation of...

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Detalles Bibliográficos
Autores principales: Arnold, Frank, Mahaddalkar, Pallavi U, Kraus, Johann M., Zhong, Xiaowei, Bergmann, Wendy, Srinivasan, Dharini, Gout, Johann, Roger, Elodie, Beutel, Alica K., Zizer, Eugen, Tharehalli, Umesh, Daiss, Nora, Russell, Ronan, Perkhofer, Lukas, Oellinger, Rupert, Lin, Qiong, Azoitei, Ninel, Weiss, Frank‐Ulrich, Lerch, Markus M., Liebau, Stefan, Katz, Sarah‐Fee, Lechel, André, Rad, Roland, Seufferlein, Thomas, Kestler, Hans A., Ott, Michael, Sharma, Amar Deep, Hermann, Patrick C., Kleger, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292873/
https://www.ncbi.nlm.nih.gov/pubmed/34306986
http://dx.doi.org/10.1002/advs.202100626

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