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I know your face but can’t remember your name: Age-related differences in the FNAME-12NL

OBJECTIVE: The Face-Name Associative Memory test (FNAME) has recently received attention as a test for early diagnosis of Alzheimer’s disease. So far, however, there has been no systematic investigation of the effects of aging. Here, we aimed to assess the extent to which the FNAME performance is mo...

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Autores principales: Enriquez-Geppert, S, Flores-Vázquez, J F, Lietz, M, Garcia-Pimenta, M, Andrés, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292925/
https://www.ncbi.nlm.nih.gov/pubmed/33159522
http://dx.doi.org/10.1093/arclin/acaa107
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author Enriquez-Geppert, S
Flores-Vázquez, J F
Lietz, M
Garcia-Pimenta, M
Andrés, P
author_facet Enriquez-Geppert, S
Flores-Vázquez, J F
Lietz, M
Garcia-Pimenta, M
Andrés, P
author_sort Enriquez-Geppert, S
collection PubMed
description OBJECTIVE: The Face-Name Associative Memory test (FNAME) has recently received attention as a test for early diagnosis of Alzheimer’s disease. So far, however, there has been no systematic investigation of the effects of aging. Here, we aimed to assess the extent to which the FNAME performance is modulated by normal ageing. METHOD: In a first step, we adapted the FNAME material to the Dutch population. In a second step, younger (n = 29) and older adults (n = 29) were compared on recall and recognition performance. RESULTS: Significant age effects on name recall were observed after the first exposure of new face-name pairs: younger adults remembered eight, whereas older adults remembered a mean of four out of twelve names. Although both age groups increased the number of recalled names with repeated face-name exposure, older adults did not catch up with the performance of the younger adults, and the age-effects remained stable. Despite of that, both age groups maintained their performance after a 30-min delay. Considering recognition, no age differences were demonstrated, and both age groups succeeded in the recognition of previously shown faces and names when presented along with distractors. CONCLUSIONS: This study presents for the first time the results of different age groups regarding cross-modal associative memory performance on the FNAME. The recall age effects support the hypothesis of age-related differences in associative memory. To use the FNAME as an early cognitive biomarker, further subscales are suggested to increase sensitivity and specificity in the clinical context.
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spelling pubmed-82929252021-07-22 I know your face but can’t remember your name: Age-related differences in the FNAME-12NL Enriquez-Geppert, S Flores-Vázquez, J F Lietz, M Garcia-Pimenta, M Andrés, P Arch Clin Neuropsychol Brief Empirical Report OBJECTIVE: The Face-Name Associative Memory test (FNAME) has recently received attention as a test for early diagnosis of Alzheimer’s disease. So far, however, there has been no systematic investigation of the effects of aging. Here, we aimed to assess the extent to which the FNAME performance is modulated by normal ageing. METHOD: In a first step, we adapted the FNAME material to the Dutch population. In a second step, younger (n = 29) and older adults (n = 29) were compared on recall and recognition performance. RESULTS: Significant age effects on name recall were observed after the first exposure of new face-name pairs: younger adults remembered eight, whereas older adults remembered a mean of four out of twelve names. Although both age groups increased the number of recalled names with repeated face-name exposure, older adults did not catch up with the performance of the younger adults, and the age-effects remained stable. Despite of that, both age groups maintained their performance after a 30-min delay. Considering recognition, no age differences were demonstrated, and both age groups succeeded in the recognition of previously shown faces and names when presented along with distractors. CONCLUSIONS: This study presents for the first time the results of different age groups regarding cross-modal associative memory performance on the FNAME. The recall age effects support the hypothesis of age-related differences in associative memory. To use the FNAME as an early cognitive biomarker, further subscales are suggested to increase sensitivity and specificity in the clinical context. Oxford University Press 2020-11-07 /pmc/articles/PMC8292925/ /pubmed/33159522 http://dx.doi.org/10.1093/arclin/acaa107 Text en © The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permission@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Empirical Report
Enriquez-Geppert, S
Flores-Vázquez, J F
Lietz, M
Garcia-Pimenta, M
Andrés, P
I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title_full I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title_fullStr I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title_full_unstemmed I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title_short I know your face but can’t remember your name: Age-related differences in the FNAME-12NL
title_sort i know your face but can’t remember your name: age-related differences in the fname-12nl
topic Brief Empirical Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292925/
https://www.ncbi.nlm.nih.gov/pubmed/33159522
http://dx.doi.org/10.1093/arclin/acaa107
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