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Effect of the Hypoxia Inducible Factor on Sorafenib Resistance of Hepatocellular Carcinoma
Sorafenib a multi-target tyrosine kinase inhibitor, is the first-line drug for treating advanced hepatocellular carcinoma (HCC). Mechanistically, it suppresses tumor angiogenesis, cell proliferation and promotes apoptosis. Although sorafenib effectively prolongs median survival rates of patients wit...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292964/ https://www.ncbi.nlm.nih.gov/pubmed/34307125 http://dx.doi.org/10.3389/fonc.2021.641522 |