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Effect of the Hypoxia Inducible Factor on Sorafenib Resistance of Hepatocellular Carcinoma

Sorafenib a multi-target tyrosine kinase inhibitor, is the first-line drug for treating advanced hepatocellular carcinoma (HCC). Mechanistically, it suppresses tumor angiogenesis, cell proliferation and promotes apoptosis. Although sorafenib effectively prolongs median survival rates of patients wit...

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Detalles Bibliográficos
Autores principales:	Zeng, Zhi, Lu, Qiliang, Liu, Yang, Zhao, Junjun, Zhang, Qian, Hu, Linjun, Shi, Zhan, Tu, Yifeng, Xiao, Zunqiang, Xu, Qiuran, Huang, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8292964/ https://www.ncbi.nlm.nih.gov/pubmed/34307125 http://dx.doi.org/10.3389/fonc.2021.641522

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