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Anti-apoptotic and Matrix Remodeling Actions of a Small Molecule Agonist of the Human Relaxin Receptor, ML290 in Mice With Unilateral Ureteral Obstruction

Diseases, such as diabetes and hypertension, often lead to chronic kidney failure. The peptide hormone relaxin has been shown to have therapeutic effects in various organs. In the present study, we tested the hypothesis that ML290, a small molecule agonist of the human relaxin receptor (RXFP1), is a...

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Detalles Bibliográficos
Autores principales:	Ng, Hooi Hooi, Soula, Mariluz, Rivas, Bryan, Wilson, Kenneth J., Marugan, Juan J., Agoulnik, Alexander I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293094/ https://www.ncbi.nlm.nih.gov/pubmed/34305630 http://dx.doi.org/10.3389/fphys.2021.650769

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