Cargando…

Cellular Effects of Rhynchophylline and Relevance to Sleep Regulation

Uncaria rhynchophylla is a plant highly used in the traditional Chinese and Japanese medicines. It has numerous health benefits, which are often attributed to its alkaloid components. Recent studies in humans show that drugs containing Uncaria ameliorate sleep quality and increase sleep time, both i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ballester Roig, Maria Neus, Leduc, Tanya, Areal, Cassandra C., Mongrain, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293156/ https://www.ncbi.nlm.nih.gov/pubmed/34207633 http://dx.doi.org/10.3390/clockssleep3020020

Ejemplares similares

Sleep-inducing effect of Rhynchophylline in EphA4 knockout mice
por: Ballester Roig, Maria Neus, et al.
Publicado: (2023)

Probing pathways by which rhynchophylline modifies sleep using spatial transcriptomics
por: Ballester Roig, Maria Neus, et al.
Publicado: (2023)

Rhynchophylline Protects Cultured Rat Neurons against Methamphetamine Cytotoxicity
por: Xu, Dan Dan, et al.
Publicado: (2012)

Rhynchophylline Attenuates Senescence of Endothelial Progenitor Cells by Enhancing Autophagy
por: Lin, Lin, et al.
Publicado: (2020)

Celastrol and Rhynchophylline in the mitigation of simulated muscle atrophy under in vitro
por: Wastag, Maksymilian, et al.
Publicado: (2022)

Recent Advances in the Anti-Inflammatory Activity of Plant-Derived Alkaloid Rhynchophylline in Neurological and Cardiovascular Diseases
por: Geetha, Rajeswari Gopal, et al.
Publicado: (2021)

Rhynchophylline Regulates Calcium Homeostasis by Antagonizing Ryanodine Receptor 2 Phosphorylation to Improve Diabetic Cardiomyopathy
por: Liu, Jiao, et al.
Publicado: (2022)

Neuroprotective Effects of Rhynchophylline Against Ischemic Brain Injury via Regulation of the Akt/mTOR and TLRs Signaling Pathways
por: Huang, Houcai, et al.
Publicado: (2014)

Systematic elucidation of the pharmacological mechanisms of Rhynchophylline for treating epilepsy via network pharmacology
por: Geng, Hua, et al.
Publicado: (2021)

A review of the current state of knowledge on sex differences in sleep and circadian phenotypes in rodents
por: Dib, Rama, et al.
Publicado: (2021)

The effects of genetic variation and environmental factors on rhynchophylline and isorhynchophylline in Uncaria macrophylla Wall. from different populations in China
por: Song, Mei-Fang, et al.
Publicado: (2018)

Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma
por: Li, Hui, et al.
Publicado: (2021)

Expression of miRNAs in Serum Exosomes versus Hippocampus in Methamphetamine-Induced Rats and Intervention of Rhynchophylline
por: Li, Han-cheng, et al.
Publicado: (2018)

Rhynchophylline ameliorates myocardial ischemia/reperfusion injury through the modulation of mitochondrial mechanisms to mediate myocardial apoptosis
por: Qin, Qiao-Ji, et al.
Publicado: (2019)

Rhynchophylline Loaded-mPEG-PLGA Nanoparticles Coated with Tween-80 for Preliminary Study in Alzheimer’s Disease
por: Xu, Ruiling, et al.
Publicado: (2020)

The effect of Neuroligin-2 absence on sleep architecture and electroencephalographic activity in mice
por: Seok, Bong Soo, et al.
Publicado: (2018)

Pharmacokinetic Interaction Study of Ketamine and Rhynchophylline in Rat Plasma by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry
por: Chen, Lianguo, et al.
Publicado: (2018)

Profiles of Metabolic Genes in Uncaria rhynchophylla and Characterization of the Critical Enzyme Involved in the Biosynthesis of Bioactive Compounds-(iso)Rhynchophylline
por: Yang, Mengquan, et al.
Publicado: (2022)

Fxr1 regulates sleep and synaptic homeostasis
por: Khlghatyan, Jivan, et al.
Publicado: (2020)

Scale-Free Dynamics of the Mouse Wakefulness and Sleep Electroencephalogram Quantified Using Wavelet-Leaders
por: Lina, Jean-Marc, et al.
Publicado: (2018)

Sustainably released nanoparticle-based rhynchophylline limits pulmonary fibrosis by inhibiting the TEK-PI3K/AKT signaling pathway
por: Wang, Shuo, et al.
Publicado: (2023)

Correction to: The effect of Neuroligin-2 absence on sleep architecture and electroencephalographic activity in mice
por: Seok, Bong Soo, et al.
Publicado: (2019)

Sleep Loss Reduces the DNA-Binding of BMAL1, CLOCK, and NPAS2 to Specific Clock Genes in the Mouse Cerebral Cortex
por: Mongrain, Valérie, et al.
Publicado: (2011)

Pharmacokinetic Comparative Study of Gastrodin and Rhynchophylline after Oral Administration of Different Prescriptions of Yizhi Tablets in Rats by an HPLC-ESI/MS Method
por: Ge, Zhaohui, et al.
Publicado: (2014)

The relevance of organelle interactions in cellular senescence
por: Huang, Jiewu, et al.
Publicado: (2022)

Structural Stabilities and Transformation Mechanism of Rhynchophylline and Isorhynchophylline by Ultra Performance Liquid Chromatography/Time-of-Flight Mass Spectrometry (UPLC/Q-TOF-MS)
por: Wu, Zhen-Feng, et al.
Publicado: (2015)

Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer's Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats
por: Zhang, Chunyuan, et al.
Publicado: (2019)

Natural product rhynchophylline prevents stress-induced hair graying by preserving melanocyte stem cells via the β2 adrenergic pathway suppression
por: Li, Xinxin, et al.
Publicado: (2023)

Morning and Evening-Type Differences in Slow Waves during NREM Sleep Reveal Both Trait and State-Dependent Phenotypes
por: Mongrain, Valérie, et al.
Publicado: (2011)

Rhynchophylline Ameliorates Endothelial Dysfunction via Src-PI3K/Akt-eNOS Cascade in the Cultured Intrarenal Arteries of Spontaneous Hypertensive Rats
por: Hao, Hui-Feng, et al.
Publicado: (2017)

Antiepileptic Effect of Uncaria rhynchophylla and Rhynchophylline Involved in the Initiation of c-Jun N-Terminal Kinase Phosphorylation of MAPK Signal Pathways in Acute Seizures of Kainic Acid-Treated Rats
por: Hsu, Hsin-Cheng, et al.
Publicado: (2013)

Cellular Compartmentalization, Glutathione Transport and Its Relevance in Some Pathologies
por: Vázquez-Meza, Héctor, et al.
Publicado: (2023)

Evaluation of Reference Genes for Normalizing RT-qPCR and Analysis of the Expression Patterns of WRKY1 Transcription Factor and Rhynchophylline Biosynthesis-Related Genes in Uncaria rhynchophylla
por: Mu, Detian, et al.
Publicado: (2023)

Solid lipid nanoparticle delivery of rhynchophylline enhanced the efficiency of allergic asthma treatment via the upregulation of suppressor of cytokine signaling 1 by repressing the p38 signaling pathway
por: Lv, Chuanfeng, et al.
Publicado: (2021)

Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor-β1-mediated Smad and mitogen-activated protein kinase signaling transductions in vivo and in vitro
por: Wang, Meng, et al.
Publicado: (2019)

Hippocampal injections of soluble amyloid-beta oligomers alter electroencephalographic activity during wake and slow-wave sleep in rats
por: Hector, Audrey, et al.
Publicado: (2023)

Lytic Release of Cellular ATP: Physiological Relevance and Therapeutic Applications
por: Grygorczyk, Ryszard, et al.
Publicado: (2021)

The Relevance of Coding Gene Polymorphysms of Cytokines and Cellular Receptors in Sepsis
por: Georgescu, Anca Meda, et al.
Publicado: (2017)

Relevance of deprivation studies in understanding rapid eye movement sleep
por: Mehta, Rachna, et al.
Publicado: (2018)

Current Probes for Imaging Carbonylation in Cellular Systems and Their Relevance to Progression of Diseases
por: Dilek, Ozlem
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_l6hsgp6ellmf9tlqa8qmdsdaig