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In Vitro Inhibition of Influenza Virus Using CRISPR/Cas13a in Chicken Cells

Advances in the field of CRISPR/Cas systems are expanding our ability to modulate cellular genomes and transcriptomes precisely and efficiently. Here, we assessed the Cas13a-mediated targeted disruption of RNA in chicken fibroblast DF1 cells. First, we developed a Tol2 transposon vector carrying the...

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Detalles Bibliográficos
Autores principales: Challagulla, Arjun, Schat, Karel A., Doran, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293360/
https://www.ncbi.nlm.nih.gov/pubmed/34201194
http://dx.doi.org/10.3390/mps4020040

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