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Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
(1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Method...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293379/ https://www.ncbi.nlm.nih.gov/pubmed/34206422 http://dx.doi.org/10.3390/pharmacy9030115 |
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author | Mangé, Anne-Sophie Pagès, Arnaud Sourdet, Sandrine Cestac, Philippe McCambridge, Cécile |
author_facet | Mangé, Anne-Sophie Pagès, Arnaud Sourdet, Sandrine Cestac, Philippe McCambridge, Cécile |
author_sort | Mangé, Anne-Sophie |
collection | PubMed |
description | (1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Methods: This cross-sectional observational study was conducted in older adults with known diabetes who underwent an outpatient frailty assessment in 2016. Glycated hemoglobin (HbA1c) target is between 6% and 7% for nonfrail patients and between 7% and 8% for frail patients. Frailty was evaluated using the Fried criteria. Prescriptions of glucose-lowering drugs were analyzed based on explicit and implicit criteria. (3) Results: Of 110 people with diabetes with an average age of 81.7 years, 67.3% were frail. They had a mean HbA1c of 7.11%. Of these patients, 60.9% had at least one drug therapy problem in their diabetes management and 40.9% were potentially overtreated. The HbA1c distribution in relation to the targets varied depending on frailty status (p < 0.002), with overly strict control in frail patients (p < 0.001). (4) Conclusions: Glycemic control does not seem to be routinely adjusted to the health of frail patients. Several factors can lead to overtreatment of these patients. |
format | Online Article Text |
id | pubmed-8293379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82933792021-07-22 Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life Mangé, Anne-Sophie Pagès, Arnaud Sourdet, Sandrine Cestac, Philippe McCambridge, Cécile Pharmacy (Basel) Article (1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Methods: This cross-sectional observational study was conducted in older adults with known diabetes who underwent an outpatient frailty assessment in 2016. Glycated hemoglobin (HbA1c) target is between 6% and 7% for nonfrail patients and between 7% and 8% for frail patients. Frailty was evaluated using the Fried criteria. Prescriptions of glucose-lowering drugs were analyzed based on explicit and implicit criteria. (3) Results: Of 110 people with diabetes with an average age of 81.7 years, 67.3% were frail. They had a mean HbA1c of 7.11%. Of these patients, 60.9% had at least one drug therapy problem in their diabetes management and 40.9% were potentially overtreated. The HbA1c distribution in relation to the targets varied depending on frailty status (p < 0.002), with overly strict control in frail patients (p < 0.001). (4) Conclusions: Glycemic control does not seem to be routinely adjusted to the health of frail patients. Several factors can lead to overtreatment of these patients. MDPI 2021-06-22 /pmc/articles/PMC8293379/ /pubmed/34206422 http://dx.doi.org/10.3390/pharmacy9030115 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mangé, Anne-Sophie Pagès, Arnaud Sourdet, Sandrine Cestac, Philippe McCambridge, Cécile Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title | Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title_full | Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title_fullStr | Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title_full_unstemmed | Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title_short | Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life |
title_sort | diabetes and frail older patients: glycemic control and prescription profile in real life |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293379/ https://www.ncbi.nlm.nih.gov/pubmed/34206422 http://dx.doi.org/10.3390/pharmacy9030115 |
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