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Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life

(1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Method...

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Autores principales: Mangé, Anne-Sophie, Pagès, Arnaud, Sourdet, Sandrine, Cestac, Philippe, McCambridge, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293379/
https://www.ncbi.nlm.nih.gov/pubmed/34206422
http://dx.doi.org/10.3390/pharmacy9030115
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author Mangé, Anne-Sophie
Pagès, Arnaud
Sourdet, Sandrine
Cestac, Philippe
McCambridge, Cécile
author_facet Mangé, Anne-Sophie
Pagès, Arnaud
Sourdet, Sandrine
Cestac, Philippe
McCambridge, Cécile
author_sort Mangé, Anne-Sophie
collection PubMed
description (1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Methods: This cross-sectional observational study was conducted in older adults with known diabetes who underwent an outpatient frailty assessment in 2016. Glycated hemoglobin (HbA1c) target is between 6% and 7% for nonfrail patients and between 7% and 8% for frail patients. Frailty was evaluated using the Fried criteria. Prescriptions of glucose-lowering drugs were analyzed based on explicit and implicit criteria. (3) Results: Of 110 people with diabetes with an average age of 81.7 years, 67.3% were frail. They had a mean HbA1c of 7.11%. Of these patients, 60.9% had at least one drug therapy problem in their diabetes management and 40.9% were potentially overtreated. The HbA1c distribution in relation to the targets varied depending on frailty status (p < 0.002), with overly strict control in frail patients (p < 0.001). (4) Conclusions: Glycemic control does not seem to be routinely adjusted to the health of frail patients. Several factors can lead to overtreatment of these patients.
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spelling pubmed-82933792021-07-22 Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life Mangé, Anne-Sophie Pagès, Arnaud Sourdet, Sandrine Cestac, Philippe McCambridge, Cécile Pharmacy (Basel) Article (1) Background: The latest recommendations for diabetes management adapt the objectives of glycemic control to the frailty profile in older patients. The purpose of this study was to evaluate the proportion of older patients with diabetes whose treatment deviates from the recommendations. (2) Methods: This cross-sectional observational study was conducted in older adults with known diabetes who underwent an outpatient frailty assessment in 2016. Glycated hemoglobin (HbA1c) target is between 6% and 7% for nonfrail patients and between 7% and 8% for frail patients. Frailty was evaluated using the Fried criteria. Prescriptions of glucose-lowering drugs were analyzed based on explicit and implicit criteria. (3) Results: Of 110 people with diabetes with an average age of 81.7 years, 67.3% were frail. They had a mean HbA1c of 7.11%. Of these patients, 60.9% had at least one drug therapy problem in their diabetes management and 40.9% were potentially overtreated. The HbA1c distribution in relation to the targets varied depending on frailty status (p < 0.002), with overly strict control in frail patients (p < 0.001). (4) Conclusions: Glycemic control does not seem to be routinely adjusted to the health of frail patients. Several factors can lead to overtreatment of these patients. MDPI 2021-06-22 /pmc/articles/PMC8293379/ /pubmed/34206422 http://dx.doi.org/10.3390/pharmacy9030115 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mangé, Anne-Sophie
Pagès, Arnaud
Sourdet, Sandrine
Cestac, Philippe
McCambridge, Cécile
Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title_full Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title_fullStr Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title_full_unstemmed Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title_short Diabetes and Frail Older Patients: Glycemic Control and Prescription Profile in Real Life
title_sort diabetes and frail older patients: glycemic control and prescription profile in real life
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293379/
https://www.ncbi.nlm.nih.gov/pubmed/34206422
http://dx.doi.org/10.3390/pharmacy9030115
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