Cargando…

Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature

Angiostrongyliasis in humans causes a range of symptoms from mild headache and myalgia to neurological complications, coma and death. Infection is caused by the consumption of raw or undercooked intermediate or paratenic hosts infected with Angiostrongylus cantonensis or via contaminated vegetables...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Leeyounjera, Darasavath, Chirapha, Chang, Ko, Vilay, Vilayvanh, Sengduangphachanh, Amphonesavanh, Adsamouth, Aphaphone, Vongsouvath, Manivanh, Keolouangkhot, Valy, Robinson, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293387/
https://www.ncbi.nlm.nih.gov/pubmed/34206193
http://dx.doi.org/10.3390/tropicalmed6030107
_version_ 1783725024949043200
author Yang, Leeyounjera
Darasavath, Chirapha
Chang, Ko
Vilay, Vilayvanh
Sengduangphachanh, Amphonesavanh
Adsamouth, Aphaphone
Vongsouvath, Manivanh
Keolouangkhot, Valy
Robinson, Matthew T.
author_facet Yang, Leeyounjera
Darasavath, Chirapha
Chang, Ko
Vilay, Vilayvanh
Sengduangphachanh, Amphonesavanh
Adsamouth, Aphaphone
Vongsouvath, Manivanh
Keolouangkhot, Valy
Robinson, Matthew T.
author_sort Yang, Leeyounjera
collection PubMed
description Angiostrongyliasis in humans causes a range of symptoms from mild headache and myalgia to neurological complications, coma and death. Infection is caused by the consumption of raw or undercooked intermediate or paratenic hosts infected with Angiostrongylus cantonensis or via contaminated vegetables or water. We describe a cluster of cases involved in the shared meal of wild raw monitor lizard in the Lao PDR. Seven males, aged 22–36 years, reported headaches, abdominal pain, arthralgia, myalgia, nausea/vomiting, diarrhea, neurological effects and loss of appetite. Five were admitted to hospital. The final diagnosis was made by clinical presentation and case history, and positive A. cantonensis PCR for two cases. All hospitalized patients recovered fully following supportive treatment. The remaining two individuals sought local home remedies and made full recovery. Whilst most published reports concern infections via consumption of molluscs, few detailed reports exist on infections that result from the consumption of reptiles and there exists little awareness in Lao PDR. This case cluster, which originates from a single meal, highlights the potential public health risk of the consumption of raw and wild-caught meat in Lao PDR and the Southeast Asia region. Without specific diagnostics, clinical history and the consideration of recent food consumption are important when evaluating patients.
format Online
Article
Text
id pubmed-8293387
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-82933872021-07-22 Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature Yang, Leeyounjera Darasavath, Chirapha Chang, Ko Vilay, Vilayvanh Sengduangphachanh, Amphonesavanh Adsamouth, Aphaphone Vongsouvath, Manivanh Keolouangkhot, Valy Robinson, Matthew T. Trop Med Infect Dis Case Report Angiostrongyliasis in humans causes a range of symptoms from mild headache and myalgia to neurological complications, coma and death. Infection is caused by the consumption of raw or undercooked intermediate or paratenic hosts infected with Angiostrongylus cantonensis or via contaminated vegetables or water. We describe a cluster of cases involved in the shared meal of wild raw monitor lizard in the Lao PDR. Seven males, aged 22–36 years, reported headaches, abdominal pain, arthralgia, myalgia, nausea/vomiting, diarrhea, neurological effects and loss of appetite. Five were admitted to hospital. The final diagnosis was made by clinical presentation and case history, and positive A. cantonensis PCR for two cases. All hospitalized patients recovered fully following supportive treatment. The remaining two individuals sought local home remedies and made full recovery. Whilst most published reports concern infections via consumption of molluscs, few detailed reports exist on infections that result from the consumption of reptiles and there exists little awareness in Lao PDR. This case cluster, which originates from a single meal, highlights the potential public health risk of the consumption of raw and wild-caught meat in Lao PDR and the Southeast Asia region. Without specific diagnostics, clinical history and the consideration of recent food consumption are important when evaluating patients. MDPI 2021-06-22 /pmc/articles/PMC8293387/ /pubmed/34206193 http://dx.doi.org/10.3390/tropicalmed6030107 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Yang, Leeyounjera
Darasavath, Chirapha
Chang, Ko
Vilay, Vilayvanh
Sengduangphachanh, Amphonesavanh
Adsamouth, Aphaphone
Vongsouvath, Manivanh
Keolouangkhot, Valy
Robinson, Matthew T.
Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title_full Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title_fullStr Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title_full_unstemmed Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title_short Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People’s Democratic Republic and Review of the Literature
title_sort cluster of angiostrongyliasis cases following consumption of raw monitor lizard in the lao people’s democratic republic and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293387/
https://www.ncbi.nlm.nih.gov/pubmed/34206193
http://dx.doi.org/10.3390/tropicalmed6030107
work_keys_str_mv AT yangleeyounjera clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT darasavathchirapha clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT changko clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT vilayvilayvanh clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT sengduangphachanhamphonesavanh clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT adsamouthaphaphone clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT vongsouvathmanivanh clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT keolouangkhotvaly clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature
AT robinsonmatthewt clusterofangiostrongyliasiscasesfollowingconsumptionofrawmonitorlizardinthelaopeoplesdemocraticrepublicandreviewoftheliterature