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Wnt-Dependent Activation of ERK Mediates Repression of Chondrocyte Fate during Calvarial Development

Wnt signaling regulates cell fate decisions in diverse contexts during development, and loss of Wnt signaling in the cranial mesenchyme results in a robust and binary cell fate switch from cranial bone to ectopic cartilage. The Extracellular signal-regulated protein kinase 1 and 2 (ERK1/2) and Wnt s...

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Detalles Bibliográficos
Autores principales: Ibarra, Beatriz A, Machen, Cody, Atit, Radhika P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293402/
https://www.ncbi.nlm.nih.gov/pubmed/34199092
http://dx.doi.org/10.3390/jdb9030023

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