Programmed Death-Ligand 1 (PD-L1) Expression Is Induced by Insulin in Pancreatic Ductal Adenocarcinoma Cells Pointing to Its Role in Immune Checkpoint Control

SIMPLE SUMMARY: Type-2 Diabetes is an established risk factor of pancreatic cancer, yet the exact modalities as well as the contribution of hyperinsulinemia are not fully understood. In our study, we explored a possible link between insulin and the immune evasion of pancreatic cancer cells. We could...

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Detalles Bibliográficos
Autores principales: Heckl, Steffen M., Mau, Franziska, Senftleben, Anke, Daunke, Tina, Beckinger, Silje, Abdullazade, Samir, Schreiber, Stefan, Röcken, Christoph, Sebens, Susanne, Schäfer, Heiner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293454/
https://www.ncbi.nlm.nih.gov/pubmed/34202040
http://dx.doi.org/10.3390/medsci9030048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293454/
https://www.ncbi.nlm.nih.gov/pubmed/34202040
http://dx.doi.org/10.3390/medsci9030048

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