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Decreased SFRP5 correlated with excessive metabolic inflammation in polycystic ovary syndrome could be reversed by metformin: implication of its role in dysregulated metabolism

BACKGROUND: Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder of heterogeneous nature. Secreted frizzled-related protein (SFRP) 5 is an anti-inflammatory adipokine implicated in metabolic homeostasis. We aimed to confirm the correlation between SFRP5, metabolic inflammation and PCOS,...

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Detalles Bibliográficos
Autores principales:	Zhang, Yi, Ran, Yuxin, Kong, Lingna, Geng, Lihong, Huang, Hua, Zhang, Hongying, Hu, Jun, Qi, Hongbo, Chen, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293500/ https://www.ncbi.nlm.nih.gov/pubmed/34284806 http://dx.doi.org/10.1186/s13048-021-00847-4

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