Animal- versus in vitro-derived antibodies: avoiding the extremes

Recent recommendations from the European Union Reference Laboratory regarding the generation of antibodies using animals have stimulated significant debate. Here, four of the scientists who served on the Scientific Advisory Committee provide clarification of their views regarding the use of animals...

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Detalles Bibliográficos
Autores principales: Bradbury, Andrew R.M., Dübel, Stefan, Knappik, Achim, Plückthun, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293942/
https://www.ncbi.nlm.nih.gov/pubmed/34281490
http://dx.doi.org/10.1080/19420862.2021.1950265
Descripción
Sumario:Recent recommendations from the European Union Reference Laboratory regarding the generation of antibodies using animals have stimulated significant debate. Here, four of the scientists who served on the Scientific Advisory Committee provide clarification of their views regarding the use of animals and in vitro platforms in antibody generation. Abbreviations: EURL ECVAM, European Union Reference Laboratory for alternatives to animal testing. ESAC, EURL ECVAM Scientific Advisory Committee

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