Mucosal Vaccination Primes NK Cell-Dependent Development of CD8(+) T Cells Against Pulmonary Brucella Infection

Past studies with the live, double-mutant B. abortus (znBAZ) strain resulted in nearly complete protection of mice against pulmonary challenge with wild-type (wt) Brucella via a dominant CD8(+) T cell response. To understand the contribution innate immune cells in priming CD8(+) T cell responses, mi...

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Detalles Bibliográficos
Autores principales: Bhagyaraj, Ella, Wang, Hongbin, Yang, Xinghong, Hoffman, Carol, Akgul, Ali, Goodwin, Zakia I., Pascual, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293993/
https://www.ncbi.nlm.nih.gov/pubmed/34305935
http://dx.doi.org/10.3389/fimmu.2021.697953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293993/
https://www.ncbi.nlm.nih.gov/pubmed/34305935
http://dx.doi.org/10.3389/fimmu.2021.697953

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