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Altered filamin A enables amyloid beta-induced tau hyperphosphorylation and neuroinflammation in Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disease with proteopathy characterized by abnormalities in amyloid beta (Aβ) and tau proteins. Defective amyloid and tau propagate and aggregate, leading to eventual amyloid plaques and neurofibrillary tangles. New data show that a third proteopathy, a...

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Detalles Bibliográficos
Autores principales: Burns, Lindsay H., Wang, Hoau-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294116/
https://www.ncbi.nlm.nih.gov/pubmed/34295950
http://dx.doi.org/10.20517/2347-8659.2017.50

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