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Secondary lymphoma development after chemotherapy in three dogs

Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog...

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Autores principales: Kim, Jeong Mi, Yi, Hong Jae, Song, Kun Ho, Seo, Kyoung Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294362/
https://www.ncbi.nlm.nih.gov/pubmed/33713569
http://dx.doi.org/10.1002/vms3.474
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author Kim, Jeong Mi
Yi, Hong Jae
Song, Kun Ho
Seo, Kyoung Won
author_facet Kim, Jeong Mi
Yi, Hong Jae
Song, Kun Ho
Seo, Kyoung Won
author_sort Kim, Jeong Mi
collection PubMed
description Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog developed generalized lymphadenopathy (GL), diagnosed as high‐grade T‐cell lymphoma by immunohistochemistry. Another spayed female Shih‐Tzu dog who was 15‐year‐old had biopsy‐induced gastrointestinal stromal tumour. Three months after being treated with Toceranib, the dog developed GL that was diagnosed by PCR for antigen receptor rearrangement as T‐cell lymphoma. An eight‐year‐old, castrated male Mongrel dog was diagnosed with mast cell tumour. The dog was treated with vinblastine, but 14 months later, GL was revealed. Fine‐needle aspiration indicated lymphoma. The owner declined to investigate the cell lineage. All three dogs developed GL after chemotherapy. We suggest that secondary lymphoma can develop in dogs after chemotherapy for a primary cancer, and thus long‐term follow‐up is necessary.
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spelling pubmed-82943622021-07-23 Secondary lymphoma development after chemotherapy in three dogs Kim, Jeong Mi Yi, Hong Jae Song, Kun Ho Seo, Kyoung Won Vet Med Sci Case Report Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog developed generalized lymphadenopathy (GL), diagnosed as high‐grade T‐cell lymphoma by immunohistochemistry. Another spayed female Shih‐Tzu dog who was 15‐year‐old had biopsy‐induced gastrointestinal stromal tumour. Three months after being treated with Toceranib, the dog developed GL that was diagnosed by PCR for antigen receptor rearrangement as T‐cell lymphoma. An eight‐year‐old, castrated male Mongrel dog was diagnosed with mast cell tumour. The dog was treated with vinblastine, but 14 months later, GL was revealed. Fine‐needle aspiration indicated lymphoma. The owner declined to investigate the cell lineage. All three dogs developed GL after chemotherapy. We suggest that secondary lymphoma can develop in dogs after chemotherapy for a primary cancer, and thus long‐term follow‐up is necessary. John Wiley and Sons Inc. 2021-03-13 /pmc/articles/PMC8294362/ /pubmed/33713569 http://dx.doi.org/10.1002/vms3.474 Text en © 2021 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Kim, Jeong Mi
Yi, Hong Jae
Song, Kun Ho
Seo, Kyoung Won
Secondary lymphoma development after chemotherapy in three dogs
title Secondary lymphoma development after chemotherapy in three dogs
title_full Secondary lymphoma development after chemotherapy in three dogs
title_fullStr Secondary lymphoma development after chemotherapy in three dogs
title_full_unstemmed Secondary lymphoma development after chemotherapy in three dogs
title_short Secondary lymphoma development after chemotherapy in three dogs
title_sort secondary lymphoma development after chemotherapy in three dogs
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294362/
https://www.ncbi.nlm.nih.gov/pubmed/33713569
http://dx.doi.org/10.1002/vms3.474
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