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Secondary lymphoma development after chemotherapy in three dogs
Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294362/ https://www.ncbi.nlm.nih.gov/pubmed/33713569 http://dx.doi.org/10.1002/vms3.474 |
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author | Kim, Jeong Mi Yi, Hong Jae Song, Kun Ho Seo, Kyoung Won |
author_facet | Kim, Jeong Mi Yi, Hong Jae Song, Kun Ho Seo, Kyoung Won |
author_sort | Kim, Jeong Mi |
collection | PubMed |
description | Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog developed generalized lymphadenopathy (GL), diagnosed as high‐grade T‐cell lymphoma by immunohistochemistry. Another spayed female Shih‐Tzu dog who was 15‐year‐old had biopsy‐induced gastrointestinal stromal tumour. Three months after being treated with Toceranib, the dog developed GL that was diagnosed by PCR for antigen receptor rearrangement as T‐cell lymphoma. An eight‐year‐old, castrated male Mongrel dog was diagnosed with mast cell tumour. The dog was treated with vinblastine, but 14 months later, GL was revealed. Fine‐needle aspiration indicated lymphoma. The owner declined to investigate the cell lineage. All three dogs developed GL after chemotherapy. We suggest that secondary lymphoma can develop in dogs after chemotherapy for a primary cancer, and thus long‐term follow‐up is necessary. |
format | Online Article Text |
id | pubmed-8294362 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82943622021-07-23 Secondary lymphoma development after chemotherapy in three dogs Kim, Jeong Mi Yi, Hong Jae Song, Kun Ho Seo, Kyoung Won Vet Med Sci Case Report Lymphoma is widely recognized in veterinary medicine. However, studies focused on secondary lymphoma after chemotherapy do not exist in veterinary medicine. An 11‐year‐old, spayed female Shih‐Tzu dog was diagnosed with mammary gland carcinoma. Twenty‐five months after carboplatin treatment, the dog developed generalized lymphadenopathy (GL), diagnosed as high‐grade T‐cell lymphoma by immunohistochemistry. Another spayed female Shih‐Tzu dog who was 15‐year‐old had biopsy‐induced gastrointestinal stromal tumour. Three months after being treated with Toceranib, the dog developed GL that was diagnosed by PCR for antigen receptor rearrangement as T‐cell lymphoma. An eight‐year‐old, castrated male Mongrel dog was diagnosed with mast cell tumour. The dog was treated with vinblastine, but 14 months later, GL was revealed. Fine‐needle aspiration indicated lymphoma. The owner declined to investigate the cell lineage. All three dogs developed GL after chemotherapy. We suggest that secondary lymphoma can develop in dogs after chemotherapy for a primary cancer, and thus long‐term follow‐up is necessary. John Wiley and Sons Inc. 2021-03-13 /pmc/articles/PMC8294362/ /pubmed/33713569 http://dx.doi.org/10.1002/vms3.474 Text en © 2021 The Authors. Veterinary Medicine and Science published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Case Report Kim, Jeong Mi Yi, Hong Jae Song, Kun Ho Seo, Kyoung Won Secondary lymphoma development after chemotherapy in three dogs |
title | Secondary lymphoma development after chemotherapy in three dogs |
title_full | Secondary lymphoma development after chemotherapy in three dogs |
title_fullStr | Secondary lymphoma development after chemotherapy in three dogs |
title_full_unstemmed | Secondary lymphoma development after chemotherapy in three dogs |
title_short | Secondary lymphoma development after chemotherapy in three dogs |
title_sort | secondary lymphoma development after chemotherapy in three dogs |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294362/ https://www.ncbi.nlm.nih.gov/pubmed/33713569 http://dx.doi.org/10.1002/vms3.474 |
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