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Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal

Coxiella burnetii, a Gram‐negative bacterium is a zoonotic agent causing coxiellosis in animals. Small ruminants and cattle are the primary reservoirs for human infection. This study was aimed to estimate the sero‐prevalence of C. burnetii in the ruminants of the selected region in Nepal. Field visi...

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Autores principales: Paudyal, Narayan, Poudel, Subash, Pandey, Durga, Khanal, Doj R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294396/
https://www.ncbi.nlm.nih.gov/pubmed/33645900
http://dx.doi.org/10.1002/vms3.458
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author Paudyal, Narayan
Poudel, Subash
Pandey, Durga
Khanal, Doj R.
author_facet Paudyal, Narayan
Poudel, Subash
Pandey, Durga
Khanal, Doj R.
author_sort Paudyal, Narayan
collection PubMed
description Coxiella burnetii, a Gram‐negative bacterium is a zoonotic agent causing coxiellosis in animals. Small ruminants and cattle are the primary reservoirs for human infection. This study was aimed to estimate the sero‐prevalence of C. burnetii in the ruminants of the selected region in Nepal. Field visits were carried out at four sites in different geographical regions of Nepal. A total of 522 sera samples were collected from 118 sheep, 242 goats and 162 cattle with the history of abortion, anoestrus and infertility. Sera were tested for the presence of antibodies against C. burnetii using a commercially available ready‐to‐use ELISA test kit. The overall true sero‐prevalence was 1.89% (95% CI: 0.33–3.45), the prevalence ranged between 4.35% and 23.21% in goats. Sero‐prevalence in goat was higher than that of cattle and sheep which ascertained that total freedom from coxiellosis cannot be confirmed in Nepal. This could complement the impacts of other infectious causes of the infertility in the farm animals as well as the public health of the farming households.
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spelling pubmed-82943962021-07-23 Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal Paudyal, Narayan Poudel, Subash Pandey, Durga Khanal, Doj R. Vet Med Sci Original Articles Coxiella burnetii, a Gram‐negative bacterium is a zoonotic agent causing coxiellosis in animals. Small ruminants and cattle are the primary reservoirs for human infection. This study was aimed to estimate the sero‐prevalence of C. burnetii in the ruminants of the selected region in Nepal. Field visits were carried out at four sites in different geographical regions of Nepal. A total of 522 sera samples were collected from 118 sheep, 242 goats and 162 cattle with the history of abortion, anoestrus and infertility. Sera were tested for the presence of antibodies against C. burnetii using a commercially available ready‐to‐use ELISA test kit. The overall true sero‐prevalence was 1.89% (95% CI: 0.33–3.45), the prevalence ranged between 4.35% and 23.21% in goats. Sero‐prevalence in goat was higher than that of cattle and sheep which ascertained that total freedom from coxiellosis cannot be confirmed in Nepal. This could complement the impacts of other infectious causes of the infertility in the farm animals as well as the public health of the farming households. John Wiley and Sons Inc. 2021-03-01 /pmc/articles/PMC8294396/ /pubmed/33645900 http://dx.doi.org/10.1002/vms3.458 Text en © 2021 The Authors Veterinary Medicine and Science Published by John Wiley & Sons Ltd https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Paudyal, Narayan
Poudel, Subash
Pandey, Durga
Khanal, Doj R.
Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title_full Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title_fullStr Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title_full_unstemmed Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title_short Sero‐detection of Coxiella burnetii infection in cattle, sheep and goats in selected regions of Nepal
title_sort sero‐detection of coxiella burnetii infection in cattle, sheep and goats in selected regions of nepal
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294396/
https://www.ncbi.nlm.nih.gov/pubmed/33645900
http://dx.doi.org/10.1002/vms3.458
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