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mTORC1 activation is not sufficient to suppress hepatic PPARα signaling or ketogenesis
The mechanistic target of rapamycin (mTOR) is often referred to as a master regulator of the cellular metabolism that can integrate the growth factor and nutrient signaling. Fasting suppresses hepatic mTORC1 activity via the activity of the tuberous sclerosis complex (TSC), a negative regulator of m...
Autores principales: | Selen, Ebru S., Wolfgang, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294577/ https://www.ncbi.nlm.nih.gov/pubmed/34146544 http://dx.doi.org/10.1016/j.jbc.2021.100884 |
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