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mTORC1 activation is not sufficient to suppress hepatic PPARα signaling or ketogenesis

The mechanistic target of rapamycin (mTOR) is often referred to as a master regulator of the cellular metabolism that can integrate the growth factor and nutrient signaling. Fasting suppresses hepatic mTORC1 activity via the activity of the tuberous sclerosis complex (TSC), a negative regulator of m...

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Detalles Bibliográficos
Autores principales: Selen, Ebru S., Wolfgang, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294577/
https://www.ncbi.nlm.nih.gov/pubmed/34146544
http://dx.doi.org/10.1016/j.jbc.2021.100884

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