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The H(+)-ATPase (V-ATPase): from proton pump to signaling complex in health and disease

A primary function of the H(+)-ATPase (or V-ATPase) is to create an electrochemical proton gradient across eukaryotic cell membranes, which energizes fundamental cellular processes. Its activity allows for the acidification of intracellular vesicles and organelles, which is necessary for many essent...

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Detalles Bibliográficos
Autores principales: Eaton, Amity F., Merkulova, Maria, Brown, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294626/
https://www.ncbi.nlm.nih.gov/pubmed/33326313
http://dx.doi.org/10.1152/ajpcell.00442.2020