Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed...

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Autores principales: Jawed, Muzamil, Khalid, Amna, Rubin, Mayer, Shafiq, Ramsha, Cemalovic, Nail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Novel ID Cases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294682/
https://www.ncbi.nlm.nih.gov/pubmed/34307734
http://dx.doi.org/10.1093/ofid/ofab343
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author Jawed, Muzamil
Khalid, Amna
Rubin, Mayer
Shafiq, Ramsha
Cemalovic, Nail
author_facet Jawed, Muzamil
Khalid, Amna
Rubin, Mayer
Shafiq, Ramsha
Cemalovic, Nail
author_sort Jawed, Muzamil
collection PubMed
description Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed to explain the pathogenesis of acute ITP, autoimmunity with the coronavirus disease 2019 (COVID-19) vaccine is still unclear and needs further research. We report a case of acute ITP after administration of the Pfizer-BioNTech mRNA COVID-19 vaccine in a patient with previously stable ITP.
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spelling pubmed-82946822021-07-22 Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP Jawed, Muzamil Khalid, Amna Rubin, Mayer Shafiq, Ramsha Cemalovic, Nail Open Forum Infect Dis Novel ID Cases Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed to explain the pathogenesis of acute ITP, autoimmunity with the coronavirus disease 2019 (COVID-19) vaccine is still unclear and needs further research. We report a case of acute ITP after administration of the Pfizer-BioNTech mRNA COVID-19 vaccine in a patient with previously stable ITP. Oxford University Press 2021-06-24 /pmc/articles/PMC8294682/ /pubmed/34307734 http://dx.doi.org/10.1093/ofid/ofab343 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Novel ID Cases
Jawed, Muzamil
Khalid, Amna
Rubin, Mayer
Shafiq, Ramsha
Cemalovic, Nail
Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title_full Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title_fullStr Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title_full_unstemmed Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title_short Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP
title_sort acute immune thrombocytopenia (itp) following covid-19 vaccination in a patient with previously stable itp
topic Novel ID Cases
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294682/
https://www.ncbi.nlm.nih.gov/pubmed/34307734
http://dx.doi.org/10.1093/ofid/ofab343
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