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Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer
Platelets extravasate from the circulation into tumor microenvironment, enable metastasis, and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor-platelet cross-talk with effective and atoxic antiplatelet agents in combination with anticancer drugs may serve as an effec...
Autores principales: | Saha, Biswajit, Mathur, Tanmay, Tronolone, James J., Chokshi, Mithil, Lokhande, Giriraj K., Selahi, Amirali, Gaharwar, Akhilesh K., Afshar-Kharghan, Vahid, Sood, Anil K., Bao, Gang, Jain, Abhishek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294767/ https://www.ncbi.nlm.nih.gov/pubmed/34290095 http://dx.doi.org/10.1126/sciadv.abg5283 |
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