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Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer

Platelets extravasate from the circulation into tumor microenvironment, enable metastasis, and confer resistance to chemotherapy in several cancers. Therefore, arresting tumor-platelet cross-talk with effective and atoxic antiplatelet agents in combination with anticancer drugs may serve as an effec...

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Detalles Bibliográficos
Autores principales: Saha, Biswajit, Mathur, Tanmay, Tronolone, James J., Chokshi, Mithil, Lokhande, Giriraj K., Selahi, Amirali, Gaharwar, Akhilesh K., Afshar-Kharghan, Vahid, Sood, Anil K., Bao, Gang, Jain, Abhishek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294767/
https://www.ncbi.nlm.nih.gov/pubmed/34290095
http://dx.doi.org/10.1126/sciadv.abg5283

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