Disorganization and degeneration of liver sympathetic innervations in nonalcoholic fatty liver disease revealed by 3D imaging

Hepatic nerves have a complex role in synchronizing liver metabolism. Here, we used three-dimensional (3D) immunoimaging to explore the integrity of the hepatic nervous system in experimental and human nonalcoholic fatty liver disease (NAFLD). We demonstrate parallel signs of mild degeneration and a...

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Detalles Bibliográficos
Autores principales: Adori, Csaba, Daraio, Teresa, Kuiper, Raoul, Barde, Swapnali, Horvathova, Lubica, Yoshitake, Takashi, Ihnatko, Robert, Valladolid-Acebes, Ismael, Vercruysse, Pauline, Wellendorf, Ashley M., Gramignoli, Roberto, Bozoky, Bela, Kehr, Jan, Theodorsson, Elvar, Cancelas, Jose A., Mravec, Boris, Jorns, Carl, Ellis, Ewa, Mulder, Jan, Uhlén, Mathias, Bark, Christina, Hökfelt, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294768/
https://www.ncbi.nlm.nih.gov/pubmed/34290096
http://dx.doi.org/10.1126/sciadv.abg5733

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