Imlifidase Desensitization in Crossmatch-positive, Highly Sensitized Kidney Transplant Recipients: Results of an International Phase 2 Trial (Highdes)

Highly HLA sensitized patients have limited access to life-saving kidney transplantation because of a paucity of immunologically suitable donors. Imlifidase is a cysteine protease that cleaves IgG leading to a rapid decrease in antibody level and inhibition of IgG-mediated injury. This study investi...

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Detalles Bibliográficos
Autores principales: Jordan, Stanley C., Legendre, Christophe, Desai, Niraj M., Lorant, Tomas, Bengtsson, Mats, Lonze, Bonnie E., Vo, Ashley A., Runström, Anna, Laxmyr, Lena, Sjöholm, Kristoffer, Schiött, Åsa, Sonesson, Elisabeth, Wood, Kathryn, Winstedt, Lena, Kjellman, Christian, Montgomery, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Clinical Science—General
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294837/
https://www.ncbi.nlm.nih.gov/pubmed/33093408
http://dx.doi.org/10.1097/TP.0000000000003496

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