The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores

All membrane fusion reactions proceed through an initial fusion pore, including calcium-triggered release of neurotransmitters and hormones. Expansion of this small pore to release cargo is energetically costly and regulated by cells, but the mechanisms are poorly understood. Here, we show that the...

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Detalles Bibliográficos
Autores principales: Wu, Zhenyong, Dharan, Nadiv, McDargh, Zachary A, Thiyagarajan, Sathish, O'Shaughnessy, Ben, Karatekin, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294851/
https://www.ncbi.nlm.nih.gov/pubmed/34190041
http://dx.doi.org/10.7554/eLife.68215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294851/
https://www.ncbi.nlm.nih.gov/pubmed/34190041
http://dx.doi.org/10.7554/eLife.68215

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