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The neuronal calcium sensor Synaptotagmin-1 and SNARE proteins cooperate to dilate fusion pores
All membrane fusion reactions proceed through an initial fusion pore, including calcium-triggered release of neurotransmitters and hormones. Expansion of this small pore to release cargo is energetically costly and regulated by cells, but the mechanisms are poorly understood. Here, we show that the...
Autores principales: | Wu, Zhenyong, Dharan, Nadiv, McDargh, Zachary A, Thiyagarajan, Sathish, O'Shaughnessy, Ben, Karatekin, Erdem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294851/ https://www.ncbi.nlm.nih.gov/pubmed/34190041 http://dx.doi.org/10.7554/eLife.68215 |
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