Cargando…

Combination of Xuesaitong and Aspirin Based on the Antiplatelet Effect and Gastrointestinal Injury: Study Protocol for a Randomized Controlled Noninferiority Trial

BACKGROUND: Aspirin is the first-line medication for prevention and treatment of coronary heart disease (CHD). However, long-term use of aspirin resulting in gastrointestinal mucosal injury and bleeding limits the regularity of medication. Xuesaitong is a marketed Chinese medicine contained main act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Bao-Chen, Xue, Chun-Miao, Lang, Rui, Weng, Wei-Liang, Wang, Xu-Jie, Lei, Zhen-Zhen, Zhang, Sha-Sha, Yang, Wen-Hua, Zhang, Wan-Tong, Hua, Guo-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294960/ https://www.ncbi.nlm.nih.gov/pubmed/34335822 http://dx.doi.org/10.1155/2021/5552506

Ejemplares similares

Inhibition of Aspirin-Induced Gastrointestinal Injury: Systematic Review and Network Meta-Analysis
por: Zhang, Wan-tong, et al.
Publicado: (2021)

Effects of Xuesaitong on the Pharmacokinetics of Losartan: An In Vivo UPLC-MS/MS Study
por: Ma, Weina, et al.
Publicado: (2019)

Xuesaitong injection treating acute myocardial infarction: A systematic review and meta-analysis
por: Hua, Yingying, et al.
Publicado: (2021)

Aspirin and antiplatelet treatments in cancer
por: Tao, Derrick L., et al.
Publicado: (2021)

Analysis of Gastrointestinal Prophylaxis in Patients Receiving Dual Antiplatelet Therapy with Aspirin and Clopidogrel
por: Morneau, Kathleen M., et al.
Publicado: (2014)

Naoxuekang, Xinnaoshutong and Xuesaitong capsules for treating stroke: a protocol for a randomised controlled trial
por: Chen, Huiling, et al.
Publicado: (2017)

Chinese preparation Xuesaitong promotes the mobilization of bone marrow mesenchymal stem cells in rats with cerebral infarction
por: Zhang, Jin-sheng, et al.
Publicado: (2016)

Immature platelets and antiplatelet therapy response to aspirin in Kawasaki disease
por: Pi, Lei, et al.
Publicado: (2018)

Aspirin vs Clopidogrel: Antiplatelet Agent of Choice for Those With Recent Bleeding or at Risk for Gastrointestinal Bleed
por: Gosavi, Siddharth, et al.
Publicado: (2023)

The Herb-Drug Interaction of Clopidogrel and Xuesaitong Dispersible Tablet by Modulation of the Pharmacodynamics and Liver Carboxylesterase 1A Metabolism
por: Ma, Shitang, et al.
Publicado: (2018)

Dissolvable polymeric microneedles loaded with aspirin for antiplatelet aggregation
por: Wang, Baorui, et al.
Publicado: (2023)

Xuesaitong injection as one adjuvant treatment of acute cerebral infarction: a systematic review and meta-analysis
por: Zhang, Xiaomeng, et al.
Publicado: (2015)

Noninferiority Testing in Clinical Trials
por: Ng, Tie-Hua
Publicado: (2014)

Tailored antiplatelet therapy can overcome clopidogrel and aspirin resistance - The BOchum CLopidogrel and Aspirin Plan (BOCLA-Plan) to improve antiplatelet therapy
por: Neubauer, Horst, et al.
Publicado: (2011)

Mapping the antiplatelet effects of clopidogrel and aspirin by modified thromboelastography
por: Hemlata,, et al.
Publicado: (2013)

Effect of Rabeprazole and Rebamipide in the Treatment of Upper Gastrointestinal Hemorrhage Associated with Dual Antiplatelet Therapy in Elderly Patients with Coronary Heart Disease
por: Jia, Rong-Jie, et al.
Publicado: (2022)

Xuesaitong Protects Podocytes from Apoptosis in Diabetic Rats through Modulating PTEN-PDK1-Akt-mTOR Pathway
por: Xue, Rui, et al.
Publicado: (2020)

Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue
por: Han, Guo-Jie, et al.
Publicado: (2022)

Defining the noninferiority margin and analysing noninferiority: An overview
por: Althunian, Turki A., et al.
Publicado: (2017)

Comparative study of xuesaitong injection and compound salvia miltiorrhizae injection in the treatment of acute cerebral infarction: a meta-analysis
por: Duan, Xiaojiao, et al.
Publicado: (2019)

Xuesaitong promotes myocardial angiogenesis in myocardial infarction mice by inhibiting MiR-3158-3p targeting Nur77
por: Liao, Jiangquan, et al.
Publicado: (2023)

Dual Antiplatelet Therapy with Clopidogrel and Aspirin Versus Aspirin Monotherapy in Patients Undergoing Coronary Artery Bypass Graft Surgery
por: Qu, Jianyu, et al.
Publicado: (2021)

Noninferiority trials
por: Snapinn, Steven M
Publicado: (2000)

Celecoxib Does Not Attenuate the Antiplatelet Effects of Aspirin and Clopidogrel in Healthy Volunteers
por: Lee, Wonjae, et al.
Publicado: (2010)

Risk of recurrent stroke and antiplatelet choice in breakthrough stroke while on aspirin
por: Kim, Joon-Tae, et al.
Publicado: (2020)

Ticagrelor as an Alternative Antiplatelet Therapy in Cardiac Patients Non-Sensitive to Aspirin
por: Khan, Hamzah, et al.
Publicado: (2020)

Linked color imaging vs Lugol chromoendoscopy for esophageal squamous cell cancer and precancerous lesion screening: A noninferiority study
por: Wang, Zi-Xin, et al.
Publicado: (2023)

A Bioassay-Based Approach for the Batch-To-Batch Consistency Evaluation of Xuesaitong Injection on a Zebrafish Thrombosis Model
por: Ma, Xiangwei, et al.
Publicado: (2021)

Sensorineural hearing loss induced by gefitinib: A CARE-compliant case report and literature reviews
por: Zhu, Bao-chen, et al.
Publicado: (2023)

Xuesaitong Soft Capsule (Chinese Patent Medicine) for the Treatment of Unstable Angina Pectoris: A Meta-Analysis and Systematic Review
por: Yang, Xiaochen, et al.
Publicado: (2013)

A Network Study of Chinese Medicine Xuesaitong Injection to Elucidate a Complex Mode of Action with Multicompound, Multitarget, and Multipathway
por: Wang, Linli, et al.
Publicado: (2013)

A Bioactive Chemical Markers Based Strategy for Quality Assessment of Botanical Drugs: Xuesaitong Injection as a Case Study
por: Yang, Zhenzhong, et al.
Publicado: (2017)

Do Aspirin and Other Antiplatelet Drugs Reduce the Mortality in Critically Ill Patients?
por: Lösche, Wolfgang, et al.
Publicado: (2012)

Determinants of Reduced Antiplatelet Effect of Aspirin in Patients with Stable Coronary Artery Disease
por: Larsen, Sanne Bøjet, et al.
Publicado: (2015)

Effects of colchicine on platelet aggregation in patients on dual antiplatelet therapy with aspirin and clopidogrel
por: Cirillo, Plinio, et al.
Publicado: (2020)

Lower Antiplatelet Effect of Aspirin in Essential Thrombocythemia than in Coronary Artery Disease
por: Pedersen, Oliver Buchhave, et al.
Publicado: (2021)

Understanding noninferiority trials
por: Hahn, Seokyung
Publicado: (2012)

Efficacy and safety of Panax notoginseng saponins (Xuesaitong) for patients with acute ischemic stroke: a systematic review and meta-analysis of randomized controlled trials
por: Shi, Xinyi, et al.
Publicado: (2023)

Does the timing of aspirin administration influence its antiplatelet effect – review of literature on chronotherapy
por: Miciak-Ławicka, Ewa, et al.
Publicado: (2018)

Dual Antiplatelet Therapy Using Cilostazol With Aspirin or Clopidogrel: Subanalysis of the CSPS.com Trial
por: Hoshino, Haruhiko, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_c0qbl69gucnea1o4rsoq5fj806