Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases

Exosomes are a type of extracellular vesicles secreted by almost all kinds of mammalian cells that shuttle “cargo” from one cell to another, indicative of its role in cell-to-cell transportation. Interestingly, exosomes are known to undergo alterations or serve as a pathway in multiple diseases, inc...

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Autores principales: Tian, Yang, Fu, Chen, Wu, Yifan, Lu, Yao, Liu, Xuemei, Zhang, Yunling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294976/
https://www.ncbi.nlm.nih.gov/pubmed/34336127
http://dx.doi.org/10.1155/2021/9965564
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author Tian, Yang
Fu, Chen
Wu, Yifan
Lu, Yao
Liu, Xuemei
Zhang, Yunling
author_facet Tian, Yang
Fu, Chen
Wu, Yifan
Lu, Yao
Liu, Xuemei
Zhang, Yunling
author_sort Tian, Yang
collection PubMed
description Exosomes are a type of extracellular vesicles secreted by almost all kinds of mammalian cells that shuttle “cargo” from one cell to another, indicative of its role in cell-to-cell transportation. Interestingly, exosomes are known to undergo alterations or serve as a pathway in multiple diseases, including neurodegenerative diseases. In the central nervous system (CNS), exosomes originating from neurons or glia cells contribute to or inhibit the progression of CNS-related diseases in special ways. In lieu of this, the current study investigated the effect of CNS cell-derived exosomes on different neurodegenerative diseases.
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spelling pubmed-82949762021-07-31 Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases Tian, Yang Fu, Chen Wu, Yifan Lu, Yao Liu, Xuemei Zhang, Yunling Oxid Med Cell Longev Review Article Exosomes are a type of extracellular vesicles secreted by almost all kinds of mammalian cells that shuttle “cargo” from one cell to another, indicative of its role in cell-to-cell transportation. Interestingly, exosomes are known to undergo alterations or serve as a pathway in multiple diseases, including neurodegenerative diseases. In the central nervous system (CNS), exosomes originating from neurons or glia cells contribute to or inhibit the progression of CNS-related diseases in special ways. In lieu of this, the current study investigated the effect of CNS cell-derived exosomes on different neurodegenerative diseases. Hindawi 2021-07-13 /pmc/articles/PMC8294976/ /pubmed/34336127 http://dx.doi.org/10.1155/2021/9965564 Text en Copyright © 2021 Yang Tian et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Tian, Yang
Fu, Chen
Wu, Yifan
Lu, Yao
Liu, Xuemei
Zhang, Yunling
Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title_full Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title_fullStr Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title_full_unstemmed Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title_short Central Nervous System Cell-Derived Exosomes in Neurodegenerative Diseases
title_sort central nervous system cell-derived exosomes in neurodegenerative diseases
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294976/
https://www.ncbi.nlm.nih.gov/pubmed/34336127
http://dx.doi.org/10.1155/2021/9965564
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